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Descriptor English: Floxuridine
Descriptor Spanish: Floxuridina
Descriptor floxuridina
Entry term(s) FUdR
fluorodesoxiuridina
Scope note: Antimetabolito antineoplásico que se metaboliza a fluorouracilo cuando se administra por inyección rápida; cuando se administra en infusión lenta, contínua e intra-arterial es convertido a monofosfato de floxuridina. Se ha usado para tratar las metástasis hepáticas de los adenocarcinomas gastrointestinales y como tratamiento paliativo de las neoplasias malignas del hígado y del tracto gastrointestinal.
Descriptor Portuguese: Floxuridina
Descriptor French: Floxuridine
Entry term(s): 2'-Désoxy-5-fluorouridine
Désoxyfluorouridine
Tree number(s): D03.383.742.680.852.300.350
D13.570.230.430.432
D13.570.685.852.300.350
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005467
Scope note: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Annotation: an antiviral & antineoplastic antimetabolite
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antimetabolites, Antineoplastic
Registry Number: 039LU44I5M
CAS Type 1 Name: Uridine, 2'-deoxy-5-fluoro-
DeCS ID: 30926
Unique ID: D005467
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Floxuridine - Preferred
Concept UI M0008626
Preferred term Floxuridine
Entry term(s) 2'-Désoxy-5-fluorouridine
Désoxyfluorouridine



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