| Descriptor English: | Rifabutin | ||||
| Descriptor Spanish: | 
                                Rifabutina                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Rifabutina | ||||
| Descriptor French: | Rifabutine | ||||
| Entry term(s): | 
                                    Alfacid Ansamycin Ansatipin Ansatipine LM 427 LM-427 LM427 Mycobutin Rifabutine  | 
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| Tree number(s): | 
                                        D03.633.400.811.650 D04.345.295.750.650  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D017828 | ||||
| Scope note: | A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients. | 
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| Allowable Qualifiers: | 
                                                                        AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Pharm Action: | 
                                                                                                    Anti-Bacterial Agents Antibiotics, Antitubercular  | 
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| Registry Number: | 1W306TDA6S | ||||
| CAS Type 1 Name: | Rifamycin XIV, 1',4-didehydro-1-deoxy-1,4-dihydro-5'-(2-methylpropyl)-1-oxo- | ||||
| Previous Indexing: | 
                                                Rifamycins (1981-1993) | 
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| Public MeSH Note: | 94; RIFABUTINE was indexed under RIFAMYCINS 1981-93 | 
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| Online Note: | use RIFABUTIN (NM) to search RIFABUTINE 1981-93 | 
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| History Note: | 94; was RIFABUTINE (NM) 1981-93 | 
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| DeCS ID: | 31068 | ||||
| Unique ID: | D017828 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 1994/01/01 | ||||
| Date of Entry: | 1993/06/04 | ||||
| Revision Date: | 2017/05/24 | 
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                                        CHEMICALS AND DRUGS
 
Heterocyclic Compounds [D03]Heterocyclic Compounds - 
                                    
CHEMICALS AND DRUGS
Polycyclic Compounds [D04]Polycyclic Compounds 
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                        Rifabutin                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Mycobutin                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        LM-427                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Alfacid                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Ansatipin                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0026934 | 
                                
| Scope note | A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients. | 
| Preferred term | Rifabutin | 
| Entry term(s) | 
                                        
                                                                                            Ansamycin                                                 Rifabutine  | 
                                
| Concept UI | 
                                        
                                        M0354269 | 
                                
| Preferred term | Mycobutin | 
| Entry term(s) | 
                                        
                                                                                            Ansatipine                                                 | 
                                
| Concept UI | 
                                        
                                        M0354268 | 
                                
| Preferred term | LM-427 | 
| Entry term(s) | 
                                        
                                                                                            LM 427                                                 LM427  | 
                                
| Concept UI | 
                                        
                                        M0475036 | 
                                
| Preferred term | Alfacid | 
| Concept UI | 
                                        
                                        M0475037 | 
                                
| Preferred term | Ansatipin | 
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