Descriptor English: Lactams, Macrocyclic
Descriptor Spanish: Lactamas Macrocíclicas
Descriptor Portuguese: Lactamas Macrocíclicas
Descriptor French: Lactames macrocycliques
Entry term(s): Ansamycins
Macrocyclic Lactams
Tree number(s): D02.065.589.327
RDF Unique Identifier:
Scope note: LACTAM-forming compounds with a ring size of approximately 1-3 dozen atoms.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 2005; ANSAMYCINS was indexed under ANTI-BACTERIAL AGENTS 1974-2004
History Note: 2005; for ANSAMYCINS use LACTAMS, MACROCYCLIC 1974-2004
DeCS ID: 38655
Unique ID: D047029
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2019/04/04
Lactams, Macrocyclic - Preferred
Concept UI M0456188
Scope note LACTAM-forming compounds with a ring size of approximately 1-3 dozen atoms.
Preferred term Lactams, Macrocyclic
Entry term(s) Macrocyclic Lactams
Ansamycins - Narrower
Concept UI M0049215
Scope note A group of LACTAMS with an aliphatic ansa chain which is linked to a BENZENE or naphthalene chromophore. Included are RIFAMYCINS, naphthomycins, geldanamycins, streptovaricins, and maytansinoids.
Preferred term Ansamycins

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