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Descriptor English: Leukotriene B4
Descriptor Spanish: Leucotrieno B4
Descriptor leucotrieno B4
Entry term(s) 5,12-HETE
5,12-diHETE
LTB4
Scope note: El principal metabolito en los leucocitos polimorfonucleares neutrófilos. Estimula la función de la célula polimorfonuclear (degranulación, formación de radicales libres centrados en el oxígeno, liberación de ácido araquidónico y metabolismo). (Dictionary of Prostaglandins and Related Compounds, 1990)
Descriptor Portuguese: Leucotrieno B4
Descriptor French: Leucotriène B4
Entry term(s): 5,12 HETE
5,12 diHETE
5,12-HETE
5,12-diHETE
B-4, Leukotriene
LTB4
Leukotriene B
Leukotriene B 4
Leukotriene B-4
Leukotrienes B
Tree number(s): D10.251.355.255.100.450.411
D10.251.355.310.166.887.411
D23.469.050.175.450.415
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007975
Scope note: The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 1HGW4DR56D
CAS Type 1 Name: 6,8,10,14-Eicosatetraenoic acid, 5,12-dihydroxy-, (S-(R*,S*-(E,Z,E,Z)))-
Previous Indexing: Arachidonic Acids (1967-1982)
Public MeSH Note: 94; was LEUKOTRIENES B 1983-93; LEUKOTRIENE B4 was see LEUKOTRIENES B 1983-93
Online Note: use LEUKOTRIENE B4 to search LEUKOTRIENES B 1983-93
History Note: 94; was LEUKOTRIENES B 1983-93; LEUKOTRIENE B4 was see LEUKOTRIENES B 1983-93
DeCS ID: 31746
Unique ID: D007975
NLM Classification: QU 90
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1983/01/01
Date of Entry: 1982/04/30
Revision Date: 2015/06/08
Leukotriene B4 - Preferred
Concept UI M0012426
Scope note The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
Preferred term Leukotriene B4
Entry term(s) B-4, Leukotriene
LTB4
Leukotriene B 4
Leukotriene B-4
Leukotrienes B - Broader
Concept UI M0012427
Preferred term Leukotrienes B
Entry term(s) Leukotriene B
5,12-diHETE - Broader
Concept UI M0012425
Preferred term 5,12-diHETE
Entry term(s) 5,12 HETE
5,12 diHETE
5,12-HETE



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