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Descriptor English: Nonoxynol
Descriptor Spanish: Nonoxinol
Descriptor Portuguese: Nonoxinol
Descriptor French: Nonoxinol
Entry term(s): Advantage S
Advantage-S
Delfen Cream
Delfen Creams
Emulgen 911
Emulgin 913
Nonoxinol
Nonoxinols
Nonoxynol 9
Nonoxynol, 1(4)-Sulfate, Sodium Salt
Nonoxynol, 4-Sulfate, Ammonium Salt
Nonoxynol-9
Nonoxynols
Nonylphenoxypolyethoxyethanol
Nonylphenoxypolyethoxyethanols
Oval, Patentex
Patentex Oval
Tree number(s): D02.033.455.250.700.620
D05.750.741.575
D25.720.741.575
J01.637.051.720.741.575
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017137
Scope note: Nonionic surfactant mixtures varying in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups. They are used as detergents, emulsifiers, wetting agents, defoaming agents, etc. Nonoxynol-9, the compound with 9 repeating ethoxy groups, is a spermatocide, formulated primarily as a component of vaginal foams and creams.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
Pharm Action: Spermatocidal Agents
Surface-Active Agents
Registry Number: 26027-38-3
CAS Type 1 Name: Poly(oxy-1,2-ethanediyl), alpha-(4-nonylphenyl)-omega-hydroxy-
Previous Indexing: Polyethylene Glycols (1975-1992)
Public MeSH Note: 1994, see NONOXYNOLS 1993; NONOXYNOLS was indexed under POLYETHYLENE GLYCOLS 1974-1992; ADVANTAGE-S was indexed under NONOXYNOL 2002-2006
History Note: 1994 (1974)
DeCS ID: 31756
Unique ID: D017137
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/19
Revision Date: 2016/07/01
Nonoxynol - Preferred
Concept UI M0026036
Scope note Nonionic surfactant mixtures varying in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups. They are used as detergents, emulsifiers, wetting agents, defoaming agents, etc. Nonoxynol-9, the compound with 9 repeating ethoxy groups, is a spermatocide, formulated primarily as a component of vaginal foams and creams.
Preferred term Nonoxynol
Entry term(s) Nonoxinol
Nonoxinols
Nonoxynols
Nonylphenoxypolyethoxyethanol
Nonylphenoxypolyethoxyethanols
Delfen Cream - Narrower
Concept UI M0350680
Preferred term Delfen Cream
Entry term(s) Delfen Creams
Emulgen 911 - Narrower
Concept UI M0026037
Preferred term Emulgen 911
Patentex Oval - Narrower
Concept UI M0534916
Preferred term Patentex Oval
Entry term(s) Oval, Patentex
Nonoxynol, 1(4)-Sulfate, Sodium Salt - Narrower
Concept UI M0329329
Preferred term Nonoxynol, 1(4)-Sulfate, Sodium Salt
Nonoxynol, 4-Sulfate, Ammonium Salt - Narrower
Concept UI M0329328
Preferred term Nonoxynol, 4-Sulfate, Ammonium Salt
Nonoxynol-9 - Narrower
Concept UI M0026039
Preferred term Nonoxynol-9
Entry term(s) Nonoxynol 9
Advantage-S - Narrower
Concept UI M0418447
Scope note A spermicidal contraceptive vaginal gel that contains nonoxynol-9 (N-9), available without prescription
Preferred term Advantage-S
Entry term(s) Advantage S
Emulgin 913 - Narrower
Concept UI M0026038
Preferred term Emulgin 913



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