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Descriptor English: Microbial Collagenase
Descriptor Spanish: Colagenasa Microbiana
Descriptor colagenasa microbiana
Entry term(s) clostridiopeptidasa A
colagenasa de Clostridium histolyticum
Scope note: Metaloproteinasa que degrada regiones helicoidales del colágeno nativo dando lugar a fragmentos pequeños. La segmentación preferencial tiene lugar en la -Gli de la secuencia -Pro-Xaa-Gli-Pro-. Se han aislado seis formas (o dos clases) de Clostridium histolycticum que presentan rectividad cruzada desde el punto de vista inmunológico, pero que poseen diferentes secuencias y especificidades. Se han encontrado otras variantes en Empedobacter collagenolyticum, Pseudomonas marinoglutinosa y especies de Vibrio y Streptomyces. EC 3.4.24.3.
Descriptor Portuguese: Colagenase Microbiana
Descriptor French: Microbial collagenase
Entry term(s): Clostridiopeptidase A
Clostridium histolyticum Collagenase
Clostridium histolyticum, Collagenase
Collagenase Clostridium histolyticum
Collagenase Like Peptidase
Collagenase, Clostridium histolyticum
Collagenase, Microbial
Collagenase-Like Peptidase
Collalysine
Nucleolysin
Peptidase, Collagenase-Like
histolyticum, Collagenase Clostridium
Tree number(s): D08.811.277.656.300.480.205.500
D08.811.277.656.675.374.205.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003012
Scope note: A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.24.3
Public MeSH Note: 94; was CLOSTRIDIUM HISTOLYTICUM COLLAGENASE 1991-93; was CLOSTRIDIOPEPTIDASE A 1963-90
Online Note: use MICROBIAL COLLAGENASE to search CLOSTRIDIUM HISTOLYTICUM COLLAGENASE 1991-93 & CLOSTRIDIOPEPTIDASE A 1966-90
History Note: 94; was CLOSTRIDIUM HISTOLYTICUM COLLAGENASE 1991-93; was CLOSTRIDIOPEPTIDASE A 1963-90
DeCS ID: 31813
Unique ID: D003012
NLM Classification: QU 136
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2014/06/12
Microbial Collagenase - Preferred
Concept UI M0004633
Scope note A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
Preferred term Microbial Collagenase
Entry term(s) Clostridiopeptidase A
Clostridium histolyticum Collagenase
Clostridium histolyticum, Collagenase
Collagenase Clostridium histolyticum
Collagenase, Clostridium histolyticum
Collagenase, Microbial
Collalysine
Nucleolysin
histolyticum, Collagenase Clostridium
Collagenase-Like Peptidase - Broader
Concept UI M0004634
Preferred term Collagenase-Like Peptidase
Entry term(s) Collagenase Like Peptidase
Peptidase, Collagenase-Like



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