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Descriptor English: Replication Origin
Descriptor Spanish: Origen de Réplica
Descriptor origen de la replicación
Entry term(s) origen de replicación
región ori
Scope note: Secuencia única de ADN de un replicón en la que se inicia y prosigue bidireccional o unidireccionalmente la REPLICACIÓN DEL ADN. Contiene los sitios en los que ocurre la primera separación de las cadenas complementarias, se sintetiza un ARN cebador y tiene lugar el cambio desde el ARN cebador a la síntesis de ADN. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed).
Descriptor Portuguese: Origem de Replicação
Descriptor French: Origine de réplication
Entry term(s): Origin of Replication
Origin, Replication
Origins, Replication
Region, ori
Regions, ori
Replication Origins
ori Region
ori Regions
Tree number(s): G05.360.340.024.220.760
G05.360.340.024.745.725
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018741
Scope note: A unique DNA sequence of a replicon at which DNA REPLICATION is initiated and proceeds bidirectionally or unidirectionally. It contains the sites where the first separation of the complementary strands occurs, a primer RNA is synthesized, and the switch from primer RNA to DNA synthesis takes place. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: DNA Replication (1969-1994)
Public MeSH Note: 95
History Note: 95
DeCS ID: 32052
Unique ID: D018741
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1995/01/01
Date of Entry: 1994/04/19
Revision Date: 2009/07/06
Replication Origin - Preferred
Concept UI M0028076
Scope note A unique DNA sequence of a replicon at which DNA REPLICATION is initiated and proceeds bidirectionally or unidirectionally. It contains the sites where the first separation of the complementary strands occurs, a primer RNA is synthesized, and the switch from primer RNA to DNA synthesis takes place. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Preferred term Replication Origin
Entry term(s) Origin of Replication
Origin, Replication
Origins, Replication
Region, ori
Regions, ori
Replication Origins
ori Region
ori Regions



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