Descriptor English: | Multiple Endocrine Neoplasia Type 1 | ||||||
Descriptor Spanish: |
Neoplasia Endocrina Múltiple Tipo 1
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Descriptor Portuguese: | Neoplasia Endócrina Múltipla Tipo 1 | ||||||
Descriptor French: | Néoplasie endocrinienne multiple de type 1 | ||||||
Entry term(s): |
Multiple Endocrine Neoplasia Type I Multiple Endocrine Neoplasms Type 1 Neoplasia, Multiple Endocrine Type 1 Neoplasms, Multiple Endocrine Type 1 Neoplasms, Multiple Endocrine Type I Wermer Syndrome |
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Tree number(s): |
C04.588.322.400.500 C04.651.600.500 C04.700.630.500 C16.320.700.630.500 C19.344.400.500 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D018761 | ||||||
Scope note: | A form of multiple endocrine neoplasia that is characterized by the combined occurrence of tumors in the PARATHYROID GLANDS, the PITUITARY GLAND, and the PANCREATIC ISLETS. The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME. This disease is due to loss-of-function of the MEN1 gene, a tumor suppressor gene (GENES, TUMOR SUPPRESSOR) on CHROMOSOME 11 (Locus: 11q13). |
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Annotation: | coordinate IM with specific endocrine/neoplasm pre-coordinates (IM) + specific histological type (IM) if pertinent |
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Allowable Qualifiers: |
BL blood BS blood supply CF cerebrospinal fluid CH chemistry CI chemically induced CL classification CN congenital CO complications DG diagnostic imaging DH diet therapy DI diagnosis DT drug therapy EC economics EH ethnology EM embryology EN enzymology EP epidemiology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PA pathology PC prevention & control PP physiopathology PS parasitology PX psychology RH rehabilitation RT radiotherapy SC secondary SU surgery TH therapy UL ultrastructure UR urine VE veterinary VI virology |
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Previous Indexing: |
Multiple Endocrine Neoplasia (1972-1994) |
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Public MeSH Note: | 95; MEA I, MEN I, & WERMER SYNDROME were see NEOPLASMS, MULTIPLE ENDOCRINE 1983-94 |
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Online Note: | use MULTIPLE ENDOCRINE NEOPLASIA to search MEA I, MEN I, & WERMER SYNDROME 1983-94 |
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History Note: | 95; MEA I, MEN I, & WERMER SYNDROME were see NEOPLASMS, MULTIPLE ENDOCRINE 1983-94 |
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Entry Version: | MULTIPLE ENDOCRINE NEOPL TYPE 1 |
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DeCS ID: | 32134 | ||||||
Unique ID: | D018761 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1995/01/01 | ||||||
Date of Entry: | 1994/05/23 | ||||||
Revision Date: | 2017/02/24 |
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DISEASES
Neoplasms [C04]Neoplasms -
DISEASES
Neoplasms [C04]Neoplasms -
DISEASES
Neoplasms [C04]Neoplasms
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Multiple Endocrine Neoplasia Type 1
- Preferred
Concept UI |
M0028096 |
Scope note | A form of multiple endocrine neoplasia that is characterized by the combined occurrence of tumors in the PARATHYROID GLANDS, the PITUITARY GLAND, and the PANCREATIC ISLETS. The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME. This disease is due to loss-of-function of the MEN1 gene, a tumor suppressor gene (GENES, TUMOR SUPPRESSOR) on CHROMOSOME 11 (Locus: 11q13). |
Preferred term | Multiple Endocrine Neoplasia Type 1 |
Entry term(s) |
Multiple Endocrine Neoplasia Type I Multiple Endocrine Neoplasms Type 1 Neoplasia, Multiple Endocrine Type 1 Neoplasms, Multiple Endocrine Type 1 Neoplasms, Multiple Endocrine Type I Wermer Syndrome |
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