Search
Descriptor English: Receptors, Polymeric Immunoglobulin
Descriptor Spanish: Receptores de Inmunoglobulina Polimérica
Descriptor receptores de inmunoglobulinas poliméricas
Scope note: Receptores Fc especializados (RECEPTORES, FC) para inmunoglobulinas poliméricas, que median la transcitosis de INMUNOGLOBULINA A e INMUNOGLOBULINA M poliméricas en las secreciones externas. Se encuentran en la superficie de las células epiteliales y de los hepatocitos. Tras la unión a con la INMUNOGLOBULINA A, el complejo ligando-receptor sufre endocitosis, transporte por vesículas y secreción en la luz por exocitosis. Antes de su liberación, la parte del receptor (COMPONENTE SECRETOR) que se une a la INMUNOGLOBULINA A es separado proteolíticamente de su porción transmembranal. (Rosen et al., The Dictionary of Immunology, 1989)
Descriptor Portuguese: Receptores de Imunoglobulina Polimérica
Descriptor French: Récepteur immunoglobuline polymérique
Entry term(s): Ig Receptor, Polymeric
Immunoglobulin Receptor, Polymeric
Immunoglobulin Receptors, Polymeric
Poly Ig Receptor
Poly-Ig Receptor
Polyimmunoglobulin Receptor
Polymeric Ig Receptor
Polymeric Immunoglobulin Receptor
Polymeric Immunoglobulin Receptors
Receptor, Poly-Ig
Receptor, Polyimmunoglobulin
Receptor, Polymeric Ig
Receptor, Polymeric Immunoglobulin
Tree number(s): D12.776.543.750.705.871.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019056
Scope note: Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Receptors, Immunologic (1989-1995)
Secretory Component (1992-1995)
Public MeSH Note: 96
History Note: 96
Entry Version: RECEPT POLY IG
DeCS ID: 32632
Unique ID: D019056
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1995/05/26
Revision Date: 2018/07/01
Receptors, Polymeric Immunoglobulin - Preferred
Concept UI M0028447
Scope note Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
Preferred term Receptors, Polymeric Immunoglobulin
Entry term(s) Ig Receptor, Polymeric
Immunoglobulin Receptor, Polymeric
Immunoglobulin Receptors, Polymeric
Poly Ig Receptor
Poly-Ig Receptor
Polyimmunoglobulin Receptor
Polymeric Ig Receptor
Polymeric Immunoglobulin Receptor
Polymeric Immunoglobulin Receptors
Receptor, Poly-Ig
Receptor, Polyimmunoglobulin
Receptor, Polymeric Ig
Receptor, Polymeric Immunoglobulin



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey