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Descriptor English: 1,2-Dimethylhydrazine
Descriptor Spanish: 1,2-Dimetilhidrazina
Descriptor 1,2-dimetilhidracina
Entry term(s) 1,2-dimetilhidrazina
Scope note: Agente alquilante de ADN. Se ha demostrado que es un potente carcinógeno. Se utiliza ampliamente para inducir tumores de colon en animales de experimentación.
Descriptor Portuguese: 1,2-Dimetilidrazina
Descriptor French: 1,2-Diméthyl-hydrazine
Entry term(s): 1,2 Dimethyl hydrazine
1,2 Dimethylhydrazine
1,2-Dimethyl-hydrazine
N,N' Dimethylhydrazine
N,N'-Dimethylhydrazine
SDMH
sym Dimethylhydrazine
sym-Dimethylhydrazine
Tree number(s): D02.442.600.400.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019813
Scope note: A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Combination: analogs & derivatives:Dimethylhydrazines
Pharm Action: Alkylating Agents
Carcinogens
Mutagens
Registry Number: IX068S9745
Previous Indexing: Dimethylhydrazines (1977-1997)
Public MeSH Note: 98; 1,2-DIMETHYLHYDRAZINE was indexed under DIMETHYLHYDRAZINES 1980-97
History Note: 98; use 1,2-DIMETHYLHYDRAZINE (NM) 1980-97
DeCS ID: 33401
Unique ID: D019813
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2013/07/08
1,2-Dimethylhydrazine - Preferred
Concept UI M0029409
Scope note A DNA alkylating agent that has been shown to be a potent carcinogen and is widely used to induce colon tumors in experimental animals.
Preferred term 1,2-Dimethylhydrazine
Entry term(s) 1,2 Dimethyl hydrazine
1,2 Dimethylhydrazine
1,2-Dimethyl-hydrazine
N,N' Dimethylhydrazine
N,N'-Dimethylhydrazine
sym-Dimethylhydrazine - Narrower
Concept UI M0029410
Preferred term sym-Dimethylhydrazine
Entry term(s) SDMH
sym Dimethylhydrazine



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