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Descriptor English: Kanamycin Kinase
Descriptor Spanish: Kanamicina Quinasa
Descriptor kanamicina cinasa
Entry term(s) fosfotransferasa de aminoglucósido
fosfotransferasa de neomicina
kanamicina quinasa
Scope note: Clase de enzimas que inactivan antibióticos aminoglucósidos-aminociclitol (AMINOGLUCÓSIDOS) por FOSFORILACIÓN específica de la región hidroxilo en 3' y/o 5'.
Descriptor Portuguese: Canamicina Quinase
Descriptor French: Kanamycin kinase
Entry term(s): 3'-Phosphotransferase, Amikacin
APH(3')-IIIa
APH(3')-IIb
APHVII
APT 3' I and II
APT-3'-I and II
Amikacin 3' Phosphotransferase
Amikacin 3'-Phosphotransferase
Aminocyclitol Phosphotransferase
Aminoglycoside 3' Phosphotransferase Type VIII
Aminoglycoside 3'-Phosphotransferase Type VIII
Aminoglycoside 3'-Phosphotransferases (I and II)
Aminoglycoside Phosphotransferase
Aminoglycoside Phosphotransferase Type III
Kanamycin Neomycin Phosphate Transferase
Kanamycin-Neomycin Phosphate Transferase
Kinase, Kanamycin
Neomycin Phosphotransferase
Neomycin Phosphotransferase II
Phosphate Transferase, Kanamycin-Neomycin
Phosphotransferase II, Neomycin
Phosphotransferase, Aminocyclitol
Phosphotransferase, Aminoglycoside
Phosphotransferase, Neomycin
Transferase, Kanamycin-Neomycin Phosphate
aphVII Gene Product
Tree number(s): D08.811.913.696.620.475
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019868
Scope note: A class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (AMINOGLYCOSIDES) by regiospecific PHOSPHORYLATION of the 3' and/or 5' hydroxyl.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.1.95
CAS Type 1 Name: ATP:kanamycin 3'-O-phosphotransferase
Previous Indexing: Kanamycin (1976-1980)
Phosphotransferases (1976-1993)
Phosphotransferases (Alcohol Group Acceptor) (1994-1997)
Public MeSH Note: 98; KANAMYCIN KINASE was indexed under PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR) 1994-97, PHOSPHOTRANSFERASES, ATP 1976-93 & KANAMYCIN 1976-80
History Note: 98; use KANAMYCIN KINASE (NM) 1980-97
DeCS ID: 33468
Unique ID: D019868
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/07/02
Revision Date: 2004/07/07
Kanamycin Kinase - Preferred
Concept UI M0029494
Scope note A class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (AMINOGLYCOSIDES) by regiospecific PHOSPHORYLATION of the 3' and/or 5' hydroxyl.
Preferred term Kanamycin Kinase
Entry term(s) 3'-Phosphotransferase, Amikacin
Amikacin 3' Phosphotransferase
Amikacin 3'-Phosphotransferase
Aminocyclitol Phosphotransferase
Aminoglycoside 3' Phosphotransferase Type VIII
Aminoglycoside 3'-Phosphotransferase Type VIII
Aminoglycoside Phosphotransferase
Kanamycin Neomycin Phosphate Transferase
Kanamycin-Neomycin Phosphate Transferase
Kinase, Kanamycin
Neomycin Phosphotransferase
Phosphate Transferase, Kanamycin-Neomycin
Phosphotransferase, Aminocyclitol
Phosphotransferase, Aminoglycoside
Phosphotransferase, Neomycin
Transferase, Kanamycin-Neomycin Phosphate
Aminoglycoside Phosphotransferase Type III - Narrower
Concept UI M0029498
Preferred term Aminoglycoside Phosphotransferase Type III
Neomycin Phosphotransferase II - Narrower
Concept UI M0029496
Preferred term Neomycin Phosphotransferase II
Entry term(s) Phosphotransferase II, Neomycin
APH(3')-IIIa - Narrower
Concept UI M0029497
Preferred term APH(3')-IIIa
APHVII - Narrower
Concept UI M0029500
Preferred term APHVII
Entry term(s) aphVII Gene Product
Aminoglycoside 3'-Phosphotransferases (I and II) - Narrower
Concept UI M0029495
Preferred term Aminoglycoside 3'-Phosphotransferases (I and II)
Entry term(s) APT 3' I and II
APT-3'-I and II
APH(3')-IIb - Narrower
Concept UI M0029499
Preferred term APH(3')-IIb



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