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Descriptor English: alpha-Methyltyrosine
Descriptor Spanish: alfa-Metiltirosina
Descriptor alfa-metiltirosina
Entry term(s) alfa-metil-p-tirosina
Scope note: Inhibidor de la enzima TIROSINA 3-MONOOXIGENASA y, por ende, de la síntesis de las catecolaminas. Se utiliza para el control de los síntomas de una excesiva estimulación simpática en los pacientes con FEOCROMOCITOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Descriptor Portuguese: alfa-Metiltirosina
Descriptor French: alpha-Méthyltyrosine
Entry term(s): DL-Tyrosine, alpha-methyl-
Demser
Hydrochloride, alpha-Methyltyrosine
Metirosine
Metyrosine
Racemetirosine
alpha MPT
alpha Methyl p tyrosine
alpha Methyl para tyrosine
alpha Methyltyrosine
alpha Methyltyrosine Hydrochloride
alpha-MPT
alpha-Methyl-p-tyrosine
alpha-Methyl-para-tyrosine
alpha-Methyltyrosine Hydrochloride
alpha-Methyltyrosine, (+,-)-Isomer
alpha-Methyltyrosine, (D,L)-Isomer
alpha-Methyltyrosine, (L)-Isomer
alpha-methyl- DL-Tyrosine
Tree number(s): D12.125.072.050.875.485.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019805
Scope note: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Combination: analogs & derivatives:Methyltyrosines
Pharm Action: Enzyme Inhibitors
Registry Number: 658-48-0
Previous Indexing: Methyltyrosines (1979-1997)
Public MeSH Note: 98; ALPHA-METHYLTYROSINE was indexed under METHYLTYROSINES 1979-97
History Note: 98; use ALPHA-METHYLTYROSINE (NM) 1979-97
DeCS ID: 33484
Unique ID: D019805
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2016/07/01
alpha-Methyltyrosine - Preferred
Concept UI M0029394
Scope note An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Preferred term alpha-Methyltyrosine
Entry term(s) alpha MPT
alpha Methyl p tyrosine
alpha Methyl para tyrosine
alpha Methyltyrosine
alpha-MPT
alpha-Methyl-p-tyrosine
alpha-Methyl-para-tyrosine
Metyrosine - Narrower
Concept UI M0329127
Preferred term Metyrosine
Entry term(s) Metirosine
alpha-Methyltyrosine, (L)-Isomer
Racemetirosine - Narrower
Concept UI M0373730
Preferred term Racemetirosine
Entry term(s) DL-Tyrosine, alpha-methyl-
alpha-Methyltyrosine, (+,-)-Isomer
alpha-Methyltyrosine, (D,L)-Isomer
alpha-methyl- DL-Tyrosine
alpha-Methyltyrosine Hydrochloride - Narrower
Concept UI M0329126
Preferred term alpha-Methyltyrosine Hydrochloride
Entry term(s) Hydrochloride, alpha-Methyltyrosine
alpha Methyltyrosine Hydrochloride
Demser - Narrower
Concept UI M0029395
Preferred term Demser



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