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Descriptor English: Pick Disease of the Brain
Descriptor Spanish: Enfermedad de Pick
Descriptor enfermedad de Pick
Entry term(s) atrofia de lóbulo encefálico circunscrita
atrofia lobar (encéfalo)
atrofia lobar cincunscrita del encéfalo
atrofia lobar del cerebro
atrofia lobar del encéfalo
atrofia lobular circunscrita encefálica
atrofia lobular del encéfalo
atrofia lobular encefálica
enfermedad de Pick del cerebro
enfermedad de Pick encefálica
Scope note: Forma infrecuente de DEMENCIA que es en ocasiones familiar. Las características clínicas incluyen AFASIA, APRAXIA, CONFUSIÓN, ANOMIA, pérdida de la memoria y deterioro de la personalidad. Este patrón está en línea con los hallazgos anatomopatológicos de atrofia circunscrita de los polos del LÓBULO FRONTAL y del LÓBULO TEMPORAL. La pérdida neuronal es máxima en el HIPOCAMPO, corteza entorrina y AMÍGDALA. Algunas neuronas corticales balonizadas contienen cuerpos argentófilos (Pick). (Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)
Descriptor Portuguese: Doença de Pick
Descriptor French: Démence de Pick
Entry term(s): Atrophies, Lobar (Brain)
Atrophy, Lobar (Brain)
Brain Atrophy, Circumscribed Lobar
Circumscribed Lobar Atrophy of the Brain
Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions
Disease, Pick
Disease, Pick's
Lobar Atrophies (Brain)
Lobar Atrophy (Brain)
Lobar Atrophy Of Brain
Lobar Atrophy of the Brain
Pick Disease
Pick Disease Of Brain
Pick's Disease
Picks Disease
Picks Disease of Brain
Tree number(s): C10.228.140.380.266.299.500
F03.615.400.380.299.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020774
Scope note: A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
SU surgery
TH therapy
UR urine
VI virology
Previous Indexing: Dementia (1966-1999)
Public MeSH Note: 2000; for PICKS DISEASE OF BRAIN see DEMENTIA 1992-1999
History Note: 2000; for PICKS DISEASE OF BRAIN use DEMENTIA 1992-1999
Entry Version: PICK DIS OF THE BRAIN
DeCS ID: 34272
Unique ID: D020774
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/05
Revision Date: 2015/06/23
Pick Disease of the Brain - Preferred
Concept UI M0005800
Scope note A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)
Preferred term Pick Disease of the Brain
Entry term(s) Atrophies, Lobar (Brain)
Atrophy, Lobar (Brain)
Brain Atrophy, Circumscribed Lobar
Circumscribed Lobar Atrophy of the Brain
Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions
Disease, Pick
Disease, Pick's
Lobar Atrophies (Brain)
Lobar Atrophy (Brain)
Lobar Atrophy Of Brain
Lobar Atrophy of the Brain
Pick Disease
Pick Disease Of Brain
Pick's Disease
Picks Disease
Picks Disease of Brain



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