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Descriptor English: Raloxifene Hydrochloride
Descriptor Spanish: Clorhidrato de Raloxifeno
Descriptor clorhidrato de raloxifeno
Entry term(s) raloxifeno
Scope note: Modulador selectivo del receptor de estrógeno (MSRE) de segunda generación utilizado para prevenir la osteoporosis en mujeres postmenopáusicas. Tiene efectos como agonista de los estrógenos en el tejido óseo y en el metabolismo del colesterol pero se comporta como antagonista completo de los estrógenos sobre la glándula mamaria y el tejido uterino.
Descriptor Portuguese: Cloridrato de Raloxifeno
Descriptor French: Chlorhydrate de raloxifène
Entry term(s): Evista
Keoxifene
Keoxifene Hydrochloride
LY 139481
LY 156758
LY-139481
LY-156758
LY139481
LY156758
Raloxifene
Raloxifene HCl
Tree number(s): D02.455.426.559.389.150.700.900.775
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020849
Scope note: A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Estrogen Antagonists
Selective Estrogen Receptor Modulators
Bone Density Conservation Agents
Registry Number: 4F86W47BR6
Previous Indexing: Piperidines (1983-1999)
Public MeSH Note: 2000; LY 139481 (now RALOXIFENE) was indexed under PIPERIDINES 1983-1999
History Note: 2000; use RALOXIFENE (NM) 1983-1999
DeCS ID: 34394
Unique ID: D020849
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2015/07/08
Raloxifene Hydrochloride - Preferred
Concept UI M0112969
Scope note A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.
Preferred term Raloxifene Hydrochloride
Entry term(s) Keoxifene Hydrochloride
Raloxifene HCl
LY-139481 - Narrower
Concept UI M0112970
Preferred term LY-139481
Entry term(s) LY 139481
LY139481
Raloxifene - Broader
Concept UI M0112968
Preferred term Raloxifene
Entry term(s) Keoxifene
Evista - Narrower
Concept UI M0333877
Preferred term Evista
LY-156758 - Narrower
Concept UI M0112964
Preferred term LY-156758
Entry term(s) LY 156758
LY156758



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