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Descriptor in English: Leptin
Descriptor in Spanish: Leptina
Descriptor in Portuguese: Leptina
Descriptor in French: Leptine
Entry term(s): Gene Product, Ob
Gene Product, Obese
Ob Gene Product
Ob Protein
Obese Gene Product
Obese Protein
Tree number(s): D06.472.699.042.500
D12.644.276.024.500
D12.644.548.011.500
D12.776.467.024.500
D23.529.024.500
Scope note: A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 2000; use LEPTIN (NM) 1995-1999
DeCS UI: 34404
Descriptor UI: D020738
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2007/07/09
Leptin - Preferred
Concept UI M0328567
Scope note A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
Preferred term Leptin
Entry term(s) Gene Product, Ob
Gene Product, Obese
Ob Gene Product
Ob Protein
Obese Gene Product
Obese Protein



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