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Descriptor English: Crotoxin
Descriptor Spanish: Crotoxina
Descriptor crotoxina
Entry term(s) crotapotina
Scope note: Complejo específico de proteínas tóxicas del veneno de Crotalus durissus terrificus (serpiente de cascabel sudamericana). Puede separarse en una fosfolipasa A y un fragmento de crotapotina, que consta de tres cadenas diferentes de aminoácidos, potencia la enzima y es específicamente neurotóxico.
Descriptor Portuguese: Crotoxina
Descriptor French: Crotoxine
Entry term(s): Crotapotin
Crotoxin A
Crotoxin B
Tree number(s): D20.888.850.960.200.210
D23.946.833.850.960.200.210
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003439
Scope note: A specific complex of toxic proteins from the venom of Crotalus durissus terrificus (South American rattlesnake). It can be separated into a phospholipase A and crotapotin fragment; the latter consists of three different amino acid chains, potentiates the enzyme, and is specifically neurotoxic.
Annotation: from a So. Amer. rattlesnake; /antag permitted but consider also ANTIVENINS
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 9007-40-3
CAS Type 1 Name: Crotoxin
Previous Indexing: Snake Venoms (1975-1977)
Snakes (1966-1974)
Venoms (1966-1974)
Public MeSH Note: 91; was see under CROTALID VENOMS 1978-90
History Note: 91(78); was see under CROTALID VENOMS 1978-90
DeCS ID: 3456
Unique ID: D003439
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/04/27
Revision Date: 2005/06/30
Crotoxin - Preferred
Concept UI M0005363
Scope note A specific complex of toxic proteins from the venom of Crotalus durissus terrificus (South American rattlesnake). It can be separated into a phospholipase A and crotapotin fragment; the latter consists of three different amino acid chains, potentiates the enzyme, and is specifically neurotoxic.
Preferred term Crotoxin
Crotapotin - Narrower
Concept UI M0005362
Preferred term Crotapotin
Crotoxin A - Narrower
Concept UI M0005364
Preferred term Crotoxin A
Crotoxin B - Narrower
Concept UI M0005365
Preferred term Crotoxin B



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