Descriptor English: | Batroxobin | ||||||
Descriptor Spanish: |
Batroxobina
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Descriptor Portuguese: | Batroxobina | ||||||
Descriptor French: | Batroxobine | ||||||
Entry term(s): |
Defibrase Defibrol Hemocoagulase Reptilase Reptilase DEF Reptilase-DEF |
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Tree number(s): |
D08.811.277.656.300.760.955.135 D08.811.277.656.959.350.955.135 D20.888.850.960.200.105 D23.946.833.850.960.200.105 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D012103 | ||||||
Scope note: | A proteolytic enzyme obtained from the venom of fer-de-lance (BOTHROPS ATROX). It is used as a plasma clotting agent for fibrinogen and for the detection of fibrinogen degradation products. The presence of heparin does not interfere with the clotting test. Hemocoagulase is a mixture containing batroxobin and factor X activator. EC 3.4.21.-. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Pharm Action: |
Fibrinolytic Agents Hemostatics |
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Registry Number: | EC 3.4.21.- | ||||||
Previous Indexing: |
Peptide Hydrolases (1969-1974) Snakes (1969-1974) Venoms (1969-1974) |
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Public MeSH Note: | 2000; see REPTILASE 1991-1999; see SERINE PROTEINASES 1975-1990; for BATROXOBIN see REPTILASE 1982-199; PLASMOCOAGULASE was indexed under COAGULASE 1979-1999 |
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History Note: | 2000(1975); for PLASMOCOAGULASE use BATROXOBIN (NM) 1979-1999 |
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DeCS ID: | 23451 | ||||||
Unique ID: | D012103 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1991/01/01 | ||||||
Date of Entry: | 1974/11/11 | ||||||
Revision Date: | 2016/07/01 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Complex Mixtures [D20]Complex Mixtures -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Batroxobin
- Preferred
Reptilase-DEF
- Narrower
Reptilase
- Narrower
Defibrase
- Narrower
Hemocoagulase
- Narrower
Concept UI |
M0018820 |
Scope note | A proteolytic enzyme obtained from the venom of fer-de-lance (BOTHROPS ATROX). It is used as a plasma clotting agent for fibrinogen and for the detection of fibrinogen degradation products. The presence of heparin does not interfere with the clotting test. Hemocoagulase is a mixture containing batroxobin and factor X activator. EC 3.4.21.-. |
Preferred term | Batroxobin |
Entry term(s) |
Defibrol |
Concept UI |
M0018821 |
Preferred term | Reptilase-DEF |
Entry term(s) |
Reptilase DEF |
Concept UI |
M0333033 |
Preferred term | Reptilase |
Concept UI |
M0333034 |
Preferred term | Defibrase |
Concept UI |
M0333035 |
Preferred term | Hemocoagulase |
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