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Descriptor English: Cycloheximide
Descriptor Spanish: Cicloheximida
Descriptor Portuguese: Cicloeximida
Descriptor French: Cycloheximide
Entry term(s): Actidione
Cicloheximide
Tree number(s): D03.383.621.808.240
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003513
Scope note: Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antifungal Agents
Protein Synthesis Inhibitors
Registry Number: 98600C0908
CAS Type 1 Name: 2,6-Piperidinedione, 4-(2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-, (1S-(1alpha(S*),3alpha,5beta))-
Public MeSH Note: 68
History Note: 68(66)
DeCS ID: 3533
Unique ID: D003513
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/28
Cycloheximide - Preferred
Concept UI M0005473
Scope note Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.
Preferred term Cycloheximide
Entry term(s) Cicloheximide
Actidione - Narrower
Concept UI M0372337
Preferred term Actidione



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