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Descriptor English: Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent
Descriptor Spanish: Hidroximetilglutaril-CoA Reductasas NAD-Dependientes
Descriptor hidroximetilglutaril-CoA reductasas NAD-dependientes
Entry term(s) HMG CoA reductasas NAD-dependientes
Scope note: Hidroximetilglutaril CoA reductasas específicas que utilizan el cofactor NAD. Esta clase de enzimas tienen un papel catabólico en microorganismos como Pseudomonas mevalonii en los que acetilan oxidativamente el ÁCIDO MVALÓNICO para formar 3-HIDROXI-METILGLUTARIL-COENZIMA A y NADH.
Descriptor Portuguese: Hidroximetilglutaril-CoA Redutases NAD-Dependentes
Descriptor French: Hydroxymethylglutaryl-CoA reductases, NAD-dependent
Entry term(s): 3-Hydroxy-3-methylglutaryl CoA-Reductase, NAD-Dependent
CoA-Reductase, NAD-Dependent 3-Hydroxy-3-methylglutaryl
HMG CoA Reductase, NAD Dependent
HMG CoA Reductase, NAD-Dependent
HMG CoA Reductases, NAD Dependent
HMG CoA Reductases, NAD-Dependent
Hydroxymethylglutaryl CoA Reductase, NAD Dependent
Hydroxymethylglutaryl CoA Reductase, NAD-Dependent
NAD-Dependent 3-Hydroxy-3-methylglutaryl CoA-Reductase
NAD-Dependent Hydroxymethylglutaryl-CoA Reductases
Tree number(s): D08.811.682.047.820.150.415.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D025781
Scope note: Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH.
Annotation: do not confuse with HYDROXYMETHYLGLUTARYL-COA-REDUCTASES, NADP-DEPENDENT
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.1.1.88
Previous Indexing: Hydroxymethylglutaryl CoA Reductases (1989-2001)
Public MeSH Note: 2002
History Note: 2002
DeCS ID: 36098
Unique ID: D025781
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2013/07/08
Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent - Preferred
Concept UI M0375836
Scope note Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH.
Preferred term Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent
Entry term(s) 3-Hydroxy-3-methylglutaryl CoA-Reductase, NAD-Dependent
CoA-Reductase, NAD-Dependent 3-Hydroxy-3-methylglutaryl
HMG CoA Reductase, NAD Dependent
HMG CoA Reductase, NAD-Dependent
HMG CoA Reductases, NAD Dependent
HMG CoA Reductases, NAD-Dependent
Hydroxymethylglutaryl CoA Reductase, NAD Dependent
Hydroxymethylglutaryl CoA Reductase, NAD-Dependent
NAD-Dependent 3-Hydroxy-3-methylglutaryl CoA-Reductase
NAD-Dependent Hydroxymethylglutaryl-CoA Reductases



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