DeCS

Descriptor English:

Vitamin B 6

Descriptor Spanish:

Vitamina B 6

Spanish from Spain

Descriptor	vitamina B 6
Entry term(s)	vitamina B6
Scope note:	El término VITAMINA B 6 hace referencia a diversas PICOLINAS (especialmente PIRIDOXINA, PIRIDOXAL y PIRIDOXAMINA) que son convertidas eficazmente en el organismo a FOSFATO DE PIRIDOXAL, coenzima para la síntesis de aminoácidos, neurotransmisores (serotonina, noradrenalina), esfingolípidos y ácido aminolevulínico. Durante la transaminación de los aminoácidos, el fosfato de piridoxal se convierte transitoriamente en fosfato de PIRIDOXAMINA. Aunque los términos piridoxina y vitamina B6 se siguen empleando frecuentemente como sinónimos, especialmente por parte de los investigadores médicos, tal práctica es errónea y, en ocasiones, engañosa (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). La mayor parte de la vitamina B6 es, en último término, degradada a ÁCIDO PIRIDÓXICO y excretado por la orina.

Descriptor Portuguese:

Vitamina B 6

Descriptor French:

Vitamine B6

Tree number(s):

D03.383.725.676.925

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D025101

Scope note:

VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine.

Annotation:

/ther use: coordinate with disease /drug ther, not /diet ther

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Entry Combination:

deficiency:Vitamin B 6 Deficiency

Pharm Action:

Vitamin B Complex

Registry Number:

8059-24-3

DeCS ID:

36121

Unique ID:

D025101

NLM Classification:

QU 187