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Descriptor English: Vitamin B 6
Descriptor Spanish: Vitamina B 6
Descriptor vitamina B 6
Entry term(s) vitamina B6
Scope note: El término VITAMINA B 6 hace referencia a diversas PICOLINAS (especialmente PIRIDOXINA, PIRIDOXAL y PIRIDOXAMINA) que son convertidas eficazmente en el organismo a FOSFATO DE PIRIDOXAL, coenzima para la síntesis de aminoácidos, neurotransmisores (serotonina, noradrenalina), esfingolípidos y ácido aminolevulínico. Durante la transaminación de los aminoácidos, el fosfato de piridoxal se convierte transitoriamente en fosfato de PIRIDOXAMINA. Aunque los términos piridoxina y vitamina B6 se siguen empleando frecuentemente como sinónimos, especialmente por parte de los investigadores médicos, tal práctica es errónea y, en ocasiones, engañosa (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). La mayor parte de la vitamina B6 es, en último término, degradada a ÁCIDO PIRIDÓXICO y excretado por la orina.
Descriptor Portuguese: Vitamina B 6
Descriptor French: Vitamine B6
Entry term(s): Vitamin B6
Tree number(s): D03.383.725.676.925
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D025101
Scope note: VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine.
Annotation: /ther use: coordinate with disease /drug ther, not /diet ther
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Combination: deficiency:Vitamin B 6 Deficiency
Pharm Action: Vitamin B Complex
Registry Number: 8059-24-3
Previous Indexing: Pyridoxine (1965-2001)
Public MeSH Note: 2002; see PYRIDOXINE 1963-2001
History Note: 2002; use PYRIDOXINE 1963-2001
DeCS ID: 36121
Unique ID: D025101
NLM Classification: QU 187
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2016/06/01
Vitamin B 6 - Preferred
Concept UI M0018248
Scope note VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine.
Preferred term Vitamin B 6
Entry term(s) Vitamin B6



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