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Descriptor English: Low Density Lipoprotein Receptor-Related Protein-2
Descriptor Spanish: Proteína 2 Relacionada con Receptor de Lipoproteína de Baja Densidad
Descriptor proteína 2 relacionada con receptores de lipoproteínas de baja densidad
Entry term(s) megalina
proteína 2 relacionada a receptor de lipoproteína de baja densidad
proteína 2 relacionada con receptores de LDL
Scope note: PROTEÍNA RELACIONADA CON EL RECEPTOR LDL encontrada en el neuroepitelio y en las células de los tubos proximales del riñón. Se la considera un receptor multiligando puesto que se une a diversos ligandos con una afinidad relativamente alta, pudiendo actuar como mediadora en la respuesta y degradación lisosomal de macromoléculas tales como: LIPOPROTEÍNAS; ENDOPEPTIDASAS; e INHIBIDORES DE LA PROTEASA.
Descriptor Portuguese: Proteína-2 Relacionada a Receptor de Lipoproteína de Baixa Densidade
Descriptor French: Protéine-2 apparentée au récepteur des LDL
Entry term(s): Antigen GP 330, Nephritis
GP330 Antigen
GP330, Renal Glycoprotein
Glycoprotein 330
Glycoprotein GP330, Renal
Heyman's Nephritis Antigen GP330
Heymann Nephritis Antigen GP330
LDL Receptor Related Protein 2
LDL-Receptor Related Protein 2
LRP 2 Receptor
LRP-2 Receptor
Low Density Lipoprotein Receptor Related Protein 2
Low-Density Lipoprotein Receptor-Related Protein-2
Megalin
Nephritis Antigen (GP330)
Renal Glycoprotein GP330
Tree number(s): D12.776.526.200
D12.776.543.750.710.450.500.200
D23.050.422.500.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D026561
Scope note: An LDL-RECEPTOR RELATED PROTEIN found in the neuroepithelium and in proximal tubular cells of the kidney. It is considered a multiligand receptor in that it binds to a variety of ligands with relatively high affinity and may function in mediating the uptake and lysosomal degradation of macromolecules such as: LIPOPROTEINS; ENDOPEPTIDASES; and PROTEASE INHIBITORS.
Annotation: note entry term Heymann Nephritis Antigen GP330: HEYMANN NEPHRITIS ANTIGENIC COMPLEX is also available
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Antigens, Surface (1984-1988)
Membrane Glycoproteins (1989-2001)
Public MeSH Note: 2012; see LDL-RECEPTOR RELATED PROTEIN 2 2002-2011; HEYMAN'S NEPHRITIS ANTIGEN GP330 was indexed under MEMBRANE GLYCOPROTEINS 1989-2001 & ANTIGENS, SURFACE 1986-1988; ANTIGEN GP330, NEPHRITIS was indexed under MEMBRANE GLYCOPROTEINS 1989-2001& ANTIGENS, SURFACE 1988; RENAL GLYCOPROTEIN GP330 was indexed under MEMBRANE GLYCOPROTEINS 1991-2001; GP330 ANTIGEN was indexed under MEMBRANE GLYCOPROTEINS 1991-2001; LPR-2 was indexed under MEMBRANE GLYCOPROTEINS 1996-2001; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEINS 2 was indexed under MEMBRANE GLYCOPROTEINS 1994-2001; MEGALIN was indexed under MEMBRANE GLYCOPROTEINS 1995-2001
History Note: 2012(2002)
DeCS ID: 36222
Unique ID: D026561
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2013/07/09
Low Density Lipoprotein Receptor-Related Protein-2 - Preferred
Concept UI M0112822
Scope note An LDL-RECEPTOR RELATED PROTEIN found in the neuroepithelium and in proximal tubular cells of the kidney. It is considered a multiligand receptor in that it binds to a variety of ligands with relatively high affinity and may function in mediating the uptake and lysosomal degradation of macromolecules such as: LIPOPROTEINS; ENDOPEPTIDASES; and PROTEASE INHIBITORS.
Preferred term Low Density Lipoprotein Receptor-Related Protein-2
Entry term(s) Antigen GP 330, Nephritis
GP330 Antigen
GP330, Renal Glycoprotein
Glycoprotein 330
Glycoprotein GP330, Renal
Heyman's Nephritis Antigen GP330
Heymann Nephritis Antigen GP330
LDL Receptor Related Protein 2
LDL-Receptor Related Protein 2
LRP 2 Receptor
LRP-2 Receptor
Low Density Lipoprotein Receptor Related Protein 2
Low-Density Lipoprotein Receptor-Related Protein-2
Megalin
Nephritis Antigen (GP330)
Renal Glycoprotein GP330



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