DeCS

Descriptor English:

Complement Pathway, Mannose-Binding Lectin

Descriptor Spanish:

Lectina de Unión a Manosa de la Vía del Complemento

Spanish from Spain

Descriptor	vía del complemento de lectina unida a manosa
Entry term(s)	vía de la lectina de activación del complemento vía del complemento de la lectina vía del complemento de lectina de unión a manosa vía del complemento de lectina unida a mananos
Scope note:	Activación del complemento desencadenada por la interacción de POLISACÁRIDOS microbianos con LECTINA DE UNIÓN A MANOSA sérica que lleva a la activación de SERINA-PROTEASAS ASOCIADAS A PROTEÍNAS DE UNIÓN A MANOSA (MASP). Como en la vía clásica, las MASP escinden el COMPLEMENTO C4 y el COMPLEMENTO C2 para formar la C3 CONVERTASA (C4B2A) y la subsiguiente C5 CONVERTASA (C4B2A3B) con la posterior escisión del COMPLEMENTO C5 y el ensamblaje del COMPLEJO DE ATAQUE A LA MEMBRANA DEL COMPLEMENTO.

Descriptor Portuguese:

Lectina de Ligação a Manose da Via do Complemento

Descriptor French:

Voie des lectines

Entry term(s):

Complement Pathway, Mannose Binding Lectin
Lectin Complement Pathway
Lectin Pathway, Mannan-Binding (Complement Activation)
Lectin Pathways, Mannan-Binding (Complement Activation)
Lectin-Complement Pathway
Lectin-Complement Pathways
Mannan Binding Lectin Complement Pathway
Mannan Binding Lectin Pathway (Complement Activation)
Mannan-Binding Lectin Complement Pathway
Mannan-Binding Lectin Pathway (Complement Activation)
Mannan-Binding Lectin Pathways (Complement Activation)
Mannose Binding Lectin Complement Pathway
Mannose-Binding Lectin Complement Pathway
Pathway, Lectin-Complement
Pathway, Mannan-Binding Lectin (Complement Activation)
Pathways, Lectin-Complement
Pathways, Mannan-Binding Lectin (Complement Activation)

Tree number(s):

G12.274.849

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D037582

Scope note:

Complement activation triggered by the interaction of microbial POLYSACCHARIDES with serum MANNOSE-BINDING LECTIN resulting in the activation of MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. As in the classical pathway, MASPs cleave COMPLEMENT C4 and COMPLEMENT C2 to form C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.

Allowable Qualifiers:

DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects

Previous Indexing:

Complement Activation (1989-2002)

Public MeSH Note:

2003

History Note:

2003

Mannose-Binding Lectin MeSH

DeCS ID:

37640

Unique ID:

D037582

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

2003/01/01

Date of Entry:

2002/07/03

Revision Date:

2016/06/23

PHENOMENA AND PROCESSES

Immune System Phenomena [G12]

Immune System Phenomena

Complement Activation [G12.274]

Complement Activation

Complement Pathway, Alternative [G12.274.695]

Complement Pathway, Alternative

Complement Pathway, Classical [G12.274.698]

Complement Pathway, Classical

Complement Pathway, Mannose-Binding Lectin [G12.274.849]

Complement Pathway, Mannose-Binding Lectin

Complement Pathway, Mannose-Binding Lectin - Preferred

Concept UI	M0413109
Scope note	Complement activation triggered by the interaction of microbial POLYSACCHARIDES with serum MANNOSE-BINDING LECTIN resulting in the activation of MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. As in the classical pathway, MASPs cleave COMPLEMENT C4 and COMPLEMENT C2 to form C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.
Preferred term	Complement Pathway, Mannose-Binding Lectin
Entry term(s)	Complement Pathway, Mannose Binding Lectin Lectin Complement Pathway Lectin Pathway, Mannan-Binding (Complement Activation) Lectin Pathways, Mannan-Binding (Complement Activation) Lectin-Complement Pathway Lectin-Complement Pathways Mannan Binding Lectin Complement Pathway Mannan Binding Lectin Pathway (Complement Activation) Mannan-Binding Lectin Complement Pathway Mannan-Binding Lectin Pathway (Complement Activation) Mannan-Binding Lectin Pathways (Complement Activation) Mannose Binding Lectin Complement Pathway Mannose-Binding Lectin Complement Pathway Pathway, Lectin-Complement Pathway, Mannan-Binding Lectin (Complement Activation) Pathways, Lectin-Complement Pathways, Mannan-Binding Lectin (Complement Activation)

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