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Descriptor English: Aryldialkylphosphatase
Descriptor Spanish: Arildialquilfosfatasa
Descriptor arildialquilfosfatasa
Entry term(s) arilalquilfosfatasa
fosfotriesterasa
paraoxonasa
Scope note: Enzima que cataliza la hidrólisis de un aril-dialquil fosfato, dando lugar a un dialquil fosfato y un alcohol arílico. Puede hidrolizar un amplio espectro de sustratos organofosforados y diversos ésteres aromáticos del ácido carboxílico. También puede intervenir en la protección enzimática de las LIPOPROTEÍNAS DE BAJA DENSIDAD frente a la modificación oxidativa y la consiguiente serie de acontecimientos que dan lugar a la formación del ATEROMA. Anteriormente se consideró que esta enzima era idéntica a la arilesterasa (EC 3.1.1.2).
Descriptor Portuguese: Arildialquilfosfatase
Descriptor French: Aryldialkylphosphatase
Entry term(s): Acid Anhydrase, Organophosphorus
Acid Anhydrolase, Organophosphorus
Acid Hydrolase, Organophosphorus
Anhydrase, OPA
Anhydrase, Organophosphorus Acid
Anhydrolase, Organophosphorus Acid
Aryl dialkyl Phosphatase
Aryl-dialkyl Phosphatase
Arylalkylphosphatase
Enzyme, OPH
Homocysteine Thiolactone Hydrolase
Hydrolase, Homocysteine Thiolactone
Hydrolase, Organophosphorus
Hydrolase, Organophosphorus Acid
OPA Anhydrase
OPH Enzyme
Organophosphorus Acid Anhydrase
Organophosphorus Acid Anhydrolase
Organophosphorus Acid Hydrolase
Organophosphorus Hydrolase
Paraoxonase
Paraoxonase 1
Paraoxonase 2
Paraoxonase-1
Paraoxonase-2
Phosphatase, Aryl-dialkyl
Thiolactone Hydrolase, Homocysteine
Tree number(s): D08.811.277.352.660.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D043303
Scope note: An enzyme which catalyzes the hydrolysis of an aryl-dialkyl phosphate to form dialkyl phosphate and an aryl alcohol. It can hydrolyze a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may also mediate an enzymatic protection of LOW DENSITY LIPOPROTEINS against oxidative modification and the consequent series of events leading to ATHEROMA formation. The enzyme was previously regarded to be identical with Arylesterase (EC 3.1.1.2).
Annotation: entry terms PARAOXONASE-1, and PARAOXONASE-2 see SCR for organism specific terms
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.8.1
Previous Indexing: Esterases (1980-2003)
Public MeSH Note: 2004; ARYLDIALKYLPHOSPHATASE was indexed under ESTERASES 1994-2003; PHOSPHORIC MONOESTER HYRDOLASES 1990-1993; PHOSPHOMONOESTERASES 1982-1989
History Note: 2004; use ARYLDIALKYLPHOSPHATASE (NM) 1980 - 2003
DeCS ID: 38151
Unique ID: D043303
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Aryldialkylphosphatase - Preferred
Concept UI M0080022
Scope note An enzyme which catalyzes the hydrolysis of an aryl-dialkyl phosphate to form dialkyl phosphate and an aryl alcohol. It can hydrolyze a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may also mediate an enzymatic protection of LOW DENSITY LIPOPROTEINS against oxidative modification and the consequent series of events leading to ATHEROMA formation. The enzyme was previously regarded to be identical with Arylesterase (EC 3.1.1.2).
Preferred term Aryldialkylphosphatase
Entry term(s) Acid Anhydrase, Organophosphorus
Acid Anhydrolase, Organophosphorus
Acid Hydrolase, Organophosphorus
Anhydrase, OPA
Anhydrase, Organophosphorus Acid
Anhydrolase, Organophosphorus Acid
Aryl dialkyl Phosphatase
Aryl-dialkyl Phosphatase
Arylalkylphosphatase
Enzyme, OPH
Homocysteine Thiolactone Hydrolase
Hydrolase, Homocysteine Thiolactone
Hydrolase, Organophosphorus
Hydrolase, Organophosphorus Acid
OPA Anhydrase
OPH Enzyme
Organophosphorus Acid Anhydrase
Organophosphorus Acid Anhydrolase
Organophosphorus Acid Hydrolase
Organophosphorus Hydrolase
Paraoxonase
Phosphatase, Aryl-dialkyl
Thiolactone Hydrolase, Homocysteine
Paraoxonase-1 - Narrower
Concept UI M0444855
Preferred term Paraoxonase-1
Entry term(s) Paraoxonase 1
Paraoxonase-2 - Narrower
Concept UI M0444856
Preferred term Paraoxonase-2
Entry term(s) Paraoxonase 2



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