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Descriptor English: Matrix Attachment Regions
Descriptor Spanish: Regiones de Fijación a la Matriz
Descriptor regiones de fijación a la matriz
Entry term(s) regiones de anclaje al esqueleto nuclear
región de fijación a la matriz
secuencia MRS
Scope note: Regiones de la CROMATINA o del ADN que se unen a la MATRIZ NUCLEAR. Se encuentran en el ADN INTERGÉNICO, especialmente flanqueando los extremos 5' de genes o grupos de genes. Muchas de las regiones que han sido aisladas contienen un motivo de secuencia bipartita denominada secuencia de reconocimiento MAR/SAR, que se unen a las PROTEÍNAS DE UNIÓN A LA REGIÓN DE FIJACIÓN A LA MATRIZ.
Descriptor Portuguese: Regiões de Interação com a Matriz
Descriptor French: Régions d'ancrage à la matrice nucléaire
Entry term(s): Element, MAR
Element, SAR
Elements, MAR
Elements, SAR
MAR Element
MAR Elements
MAR SAR Recognition Signature Sequence
MAR-SAR Recognition Signature Sequence
MRS Sequence
MRS Sequences
Matrix Attached Regions
Matrix Attachment Region
Matrix-Attached Region
Matrix-Attached Regions
Region, Matrix Attachment
Region, Matrix-Attached
Region, Scaffold Attachment
Region, Scaffold-Attached
Regions, Matrix Attachment
Regions, Matrix-Attached
Regions, Scaffold Attachment
Regions, Scaffold-Attached
SAR Element
SAR Elements
Scaffold Attached Regions
Scaffold Attachment Region
Scaffold Attachment Regions
Scaffold-Attached Region
Scaffold-Attached Regions
Sequences, MRS
Tree number(s): G02.111.570.080.534
G05.360.080.534
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D045170
Scope note: Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' ends of genes or clusters of genes. Many of the regions that have been isolated contain a bipartite sequence motif called the MAR/SAR recognition signature sequence that binds to MATRIX ATTACHMENT REGION BINDING PROTEINS.
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
PH physiology
RE radiation effects
Previous Indexing: Nuclear Matrix/metabolism (1990-2003)
Public MeSH Note: 2004
History Note: 2004
DeCS ID: 38376
Unique ID: D045170
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2011/12/12
Matrix Attachment Regions - Preferred
Concept UI M0447380
Scope note Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' ends of genes or clusters of genes. Many of the regions that have been isolated contain a bipartite sequence motif called the MAR/SAR recognition signature sequence that binds to MATRIX ATTACHMENT REGION BINDING PROTEINS.
Preferred term Matrix Attachment Regions
Entry term(s) Element, MAR
Element, SAR
Elements, MAR
Elements, SAR
MAR Element
MAR Elements
Matrix Attached Regions
Matrix Attachment Region
Matrix-Attached Region
Matrix-Attached Regions
Region, Matrix Attachment
Region, Matrix-Attached
Region, Scaffold Attachment
Region, Scaffold-Attached
Regions, Matrix Attachment
Regions, Matrix-Attached
Regions, Scaffold Attachment
Regions, Scaffold-Attached
SAR Element
SAR Elements
Scaffold Attached Regions
Scaffold Attachment Region
Scaffold Attachment Regions
Scaffold-Attached Region
Scaffold-Attached Regions
MRS Sequence - Narrower
Concept UI M0448643
Preferred term MRS Sequence
Entry term(s) MAR SAR Recognition Signature Sequence
MAR-SAR Recognition Signature Sequence
MRS Sequences
Sequences, MRS



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