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Descriptor English: Eosinophil Major Basic Protein
Descriptor Spanish: Proteína Mayor Básica del Eosinófilo
Descriptor proteína básica principal de los eosinófilos
Entry term(s) proteína básica de los eosinófilos
proteína básica del eosinófilo
Scope note: Una de las diversas proteínas básicas de los gránulos citoplásmicos del EOSINÓFILO. La proteína básica principal es un péptido citotóxico de 14 kDa, con un pI de 10,9. Además de sus efectos citotóxicos directos, estimula la secreción de diversos MEDIADORES DE LA INFLAMACIÓN.
Descriptor Portuguese: Proteína Básica Maior de Eosinófilos
Descriptor French: Protéine basique majeure de l'éosinophile
Entry term(s): Basic Protein, Eosinophil
Eosinophil Basic Protein
Eosinophil MBP Protein
MBP Protein, Eosinophil
Major Basic Protein, Eosinophil
Tree number(s): D12.776.124.486.379.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D047093
Scope note: One of several basic proteins released from EOSINOPHIL cytoplasmic granules. Eosinophil major basic protein is a 14-kDa cytotoxic peptide with a pI of 10.9. In addition to its direct cytotoxic effects, it stimulates the release of variety of INFLAMMATION MEDIATORS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Immunologic Factors
Registry Number: EC 3.1.27.-
Previous Indexing: Blood Proteins (1981-2004)
Ribonucleases (1981-2004)
Public MeSH Note: 2005; EOSINOPHIL BASIC PROTEIN was indexed under BLOOD PROTEINS & RIBONUCLEASES 1981-2004
History Note: 2005(1981)
DeCS ID: 38755
Unique ID: D047093
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2005/06/30
Eosinophil Major Basic Protein - Preferred
Concept UI M0069649
Scope note One of several basic proteins released from EOSINOPHIL cytoplasmic granules. Eosinophil major basic protein is a 14-kDa cytotoxic peptide with a pI of 10.9. In addition to its direct cytotoxic effects, it stimulates the release of variety of INFLAMMATION MEDIATORS.
Preferred term Eosinophil Major Basic Protein
Entry term(s) Basic Protein, Eosinophil
Eosinophil Basic Protein
Eosinophil MBP Protein
MBP Protein, Eosinophil
Major Basic Protein, Eosinophil



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