| Descriptor English: | Dichlororibofuranosylbenzimidazole | ||||||
| Descriptor Spanish: |
Diclororribofuranosil Benzoimidazol
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| Descriptor Portuguese: | Diclororribofuranosilbenzimidazol | ||||||
| Descriptor French: | Dichlororibofuranosylbenzimidazole | ||||||
| Entry term(s): |
5,6 Dichloro 1 beta D ribofuranosyl 1 H benzimidazol 5,6 Dichloro 1 beta ribofuranosylbenzimidazole 5,6-Dichloro-1-beta-D-ribofuranosyl-1-H-benzimidazol 5,6-Dichloro-1-beta-ribofuranosylbenzimidazole DRB Dichlorobenzimidazole Riboside Riboside, Dichlorobenzimidazole |
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| Tree number(s): |
D13.570.800.330 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D004004 | ||||||
| Scope note: | An RNA polymerase II transcriptional inhibitor. This compound terminates transcription prematurely by selective inhibition of RNA synthesis. It is used in research to study underlying mechanisms of cellular regulation. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Enzyme Inhibitors Nucleic Acid Synthesis Inhibitors |
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| Registry Number: | 53-85-0 | ||||||
| CAS Type 1 Name: | 1H-Benzimidazole, 5,6-dichloro-1-beta-D-ribofuranosyl- | ||||||
| Previous Indexing: |
Benzimidazoles (1966-1978) Nucleosides (1966-1970) Ribonucleosides (1971-1978) |
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| Public MeSH Note: | 91; was see under RIBONUCLEOSIDES 1979-90 |
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| History Note: | 91(79); was see under RIBONUCLEOSIDES 1979-90 |
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| Entry Version: | DCRFB |
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| DeCS ID: | 4038 | ||||||
| Unique ID: | D004004 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1978/03/08 | ||||||
| Revision Date: | 1998/06/10 |
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Dichlororibofuranosylbenzimidazole
- Preferred
| Concept UI |
M0006279 |
| Scope note | An RNA polymerase II transcriptional inhibitor. This compound terminates transcription prematurely by selective inhibition of RNA synthesis. It is used in research to study underlying mechanisms of cellular regulation. |
| Preferred term | Dichlororibofuranosylbenzimidazole |
| Entry term(s) |
5,6 Dichloro 1 beta D ribofuranosyl 1 H benzimidazol 5,6 Dichloro 1 beta ribofuranosylbenzimidazole 5,6-Dichloro-1-beta-D-ribofuranosyl-1-H-benzimidazol 5,6-Dichloro-1-beta-ribofuranosylbenzimidazole DRB Dichlorobenzimidazole Riboside Riboside, Dichlorobenzimidazole |
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