Search
Descriptor English: Alkylating Agents
Descriptor Spanish: Alquilantes
Descriptor Portuguese: Alquilantes
Descriptor French: Agents alcoylants
Entry term(s): Agent, Alkylating
Agents, Alkylating
Alkylating Agent
Alkylator
Alkylators
Tree number(s): D27.505.519.124
D27.888.569.035
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000477
Scope note: Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 66
History Note: 66(64)
DeCS ID: 479
Unique ID: D000477
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27
Alkylating Agents - Preferred
Concept UI M0000721
Scope note Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
Preferred term Alkylating Agents
Entry term(s) Agent, Alkylating
Agents, Alkylating
Alkylating Agent
Alkylator
Alkylators



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey