| Descriptor English: | Alkylating Agents | ||||||
| Descriptor Spanish: |
Alquilantes
| ||||||
| Descriptor Portuguese: | Alquilantes | ||||||
| Descriptor French: | Agents alcoylants | ||||||
| Entry term(s): |
Agent, Alkylating Agents, Alkylating Alkylating Agent Alkylator Alkylators |
||||||
| Tree number(s): |
D27.505.519.124 D27.888.569.035 |
||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000477 | ||||||
| Scope note: | Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. |
||||||
| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
||||||
| Public MeSH Note: | 66 |
||||||
| History Note: | 66(64) |
||||||
| DeCS ID: | 479 | ||||||
| Unique ID: | D000477 | ||||||
| NLM Classification: | QV 269 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1966/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2020/05/27 |
-
-
CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses -
CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses
|
|
Alkylating Agents
- Preferred
| Concept UI |
M0000721 |
| Scope note | Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. |
| Preferred term | Alkylating Agents |
| Entry term(s) |
Agent, Alkylating Agents, Alkylating Alkylating Agent Alkylator Alkylators |
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey
