| Descriptor English: | Estrone | ||||||
| Descriptor Spanish: | 
                                Estrona                                        
                                        
                                                                                                                            
                                            
  | ||||||
| Descriptor Portuguese: | Estrona | ||||||
| Descriptor French: | Oestrone | ||||||
| Entry term(s): | 
                                    Estrone, (+-)-Isomer Estrone, (8 alpha)-Isomer Estrone, (9 beta)-Isomer Estrovarin Folliculin (Hormone) Kestrone Unigen Wehgen  | 
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| Tree number(s): | 
                                        D04.210.500.365.415.414 D04.210.500.578.502.497 D06.472.040.502.497 D06.472.334.851.437.996  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D004970 | ||||||
| Scope note: | An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women. | 
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| Allowable Qualifiers: | 
                                                                        AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Pharm Action: | 
                                                                                                    Estrogens | 
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| Registry Number: | 2DI9HA706A | ||||||
| CAS Type 1 Name: | Estra-1,3,5(10)-trien-17-one, 3-hydroxy- | ||||||
| DeCS ID: | 5062 | ||||||
| Unique ID: | D004970 | ||||||
| NLM Classification: | WP 522 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1966/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2017/05/24 | 
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                                        CHEMICALS AND DRUGS
 
Polycyclic Compounds [D04]Polycyclic Compounds - 
                                    
CHEMICALS AND DRUGS
Polycyclic Compounds [D04]Polycyclic Compounds 
| 
                                                             | 
                                
                        
                                                                    
                        Estrone                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Estrone, (8 alpha)-Isomer                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Estrone, (9 beta)-Isomer                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Wehgen                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Folliculin (Hormone)                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Kestrone                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Unigen                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Estrone, (+-)-Isomer                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Estrovarin                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0007798 | 
                                
| Scope note | An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women. | 
| Preferred term | Estrone | 
| Concept UI | 
                                        
                                        M0330350 | 
                                
| Preferred term | Estrone, (8 alpha)-Isomer | 
| Concept UI | 
                                        
                                        M0330348 | 
                                
| Preferred term | Estrone, (9 beta)-Isomer | 
| Concept UI | 
                                        
                                        M0477789 | 
                                
| Preferred term | Wehgen | 
| Concept UI | 
                                        
                                        M0369352 | 
                                
| Preferred term | Folliculin (Hormone) | 
| Concept UI | 
                                        
                                        M0477787 | 
                                
| Preferred term | Kestrone | 
| Concept UI | 
                                        
                                        M0477788 | 
                                
| Preferred term | Unigen | 
| Concept UI | 
                                        
                                        M0330349 | 
                                
| Preferred term | Estrone, (+-)-Isomer | 
| Concept UI | 
                                        
                                        M0369353 | 
                                
| Preferred term | Estrovarin | 
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