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Descriptor English: Aquaporin 2
Descriptor Spanish: Acuaporina 2
Descriptor acuaporina 2
Scope note: Proteína específica de los canales de agua que se expresa en los TÚBULOS COLECTORES RENALES. La translocación de la acuaporina 2 a la MEMBRANA PLASMÁTICA apical está regulada por la VASOPRESINA, y se han implicado a las MUTACIONES de AQP2 en diversos trastornos renales, como la DIABETES INSÍPIDA.
Descriptor Portuguese: Aquaporina 2
Descriptor French: Aquaporine-2
Entry term(s): AQP2 Protein
Aquaporin CD
Aquaporin-2
Aquaporin-CD
Water Channel Of Collecting Duct
Tree number(s): D12.776.157.530.400.500.040.437
D12.776.543.550.450.730.040.437
D12.776.543.585.400.730.040.530
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051399
Scope note: Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA MEMBRANE is regulated by VASOPRESSIN, and MUTATIONS in AQP2 have been implicated in a variety of kidney disorders including DIABETES INSIPIDUS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; AQUAPORIN 2 was indexed under AQUAPORINS 1999-2005, & under ION CHANNELS 1995-1998, & under MEMBRANE PROTEINS 1993-1994
History Note: 2006(1993)
Related: Diabetes Insipidus, Nephrogenic MeSH
DeCS ID: 50856
Unique ID: D051399
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/07/01
Aquaporin 2 - Preferred
Concept UI M0213077
Scope note Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA MEMBRANE is regulated by VASOPRESSIN, and MUTATIONS in AQP2 have been implicated in a variety of kidney disorders including DIABETES INSIPIDUS.
Preferred term Aquaporin 2
Entry term(s) AQP2 Protein
Aquaporin CD
Aquaporin-2
Aquaporin-CD
Water Channel Of Collecting Duct



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