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Descriptor English: NF-kappa B p50 Subunit
Descriptor Spanish: Subunidad p50 de NF-kappa B
Descriptor subunidad p50 de NF-kappa B
Scope note: Componente del factor de transcripción NF-kappa B. Surge a partir de un proceso proteolítico del precursor de la proteína NF-kappa B p105, y es capaz de formar complejos diméricos consigo mismo o con el FACTOR DE TRANSCRIPCIÓN RELA. Regula la expresión de GENES involucrados en las respuestas inflamatoria e inmunológica.
Descriptor Portuguese: Subunidade p50 de NF-kappa B
Descriptor French: Sous-unité p50 de NF-kappa B
Entry term(s): NF kappa B p105 Precursor Protein
NF kappa B p50
NF kappa B p50 Subunit
NF kappaB 50 kDa
NF-kappa B p105 Precursor Protein
NF-kappa B p50
NF-kappaB 50-kDa
NFKB1 Transcription Factor
Transcription Factor, NFKB1
p50, NF-kappa B
Tree number(s): D12.776.260.600.124
D12.776.660.600.124
D12.776.930.600.124
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D052002
Scope note: A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p105 precursor protein and is capable of forming dimeric complexes with itself or with TRANSCRIPTION FACTOR RELA. It regulates expression of GENES involved in immune and inflammatory responses.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; NF-KAPPA B P50 SUBUNIT was indexed under NF-KAPPA B & PROTEIN PRECURSORS 1992-2005
History Note: 2006(1992)
DeCS ID: 51021
Unique ID: D052002
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2005/07/19
NF-kappa B p50 Subunit - Preferred
Concept UI M0195386
Scope note A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p105 precursor protein and is capable of forming dimeric complexes with itself or with TRANSCRIPTION FACTOR RELA. It regulates expression of GENES involved in immune and inflammatory responses.
Preferred term NF-kappa B p50 Subunit
Entry term(s) NF kappa B p50
NF kappa B p50 Subunit
NF kappaB 50 kDa
NF-kappa B p50
NF-kappaB 50-kDa
NFKB1 Transcription Factor
Transcription Factor, NFKB1
p50, NF-kappa B
NF-kappa B p105 Precursor Protein - Related but not broader or narrower
Concept UI M0198807
Scope note NF-kappa B p105 precursor protein is constitutively processed by the PROTEASOME to produce NF-kappa B p50 subunit. It helps regulate map kinase signaling through its association with Map3k8 protein.
Preferred term NF-kappa B p105 Precursor Protein
Entry term(s) NF kappa B p105 Precursor Protein



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