| Descriptor English: | Receptor, Interferon alpha-beta | ||||||
| Descriptor Spanish: |
Receptor de Interferón alfa y beta
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| Descriptor Portuguese: | Receptor de Interferon alfa e beta | ||||||
| Descriptor French: | Récepteur à l'interféron alpha-bêta | ||||||
| Entry term(s): |
IFN alphabetaR IFN-alphaR IFN-alphabetaR IFNAR1 Subunit, Interferon alpha beta Receptor IFNAR1 Subunit, Interferon alpha-beta Receptor IFNAR2 Subunit, Interferon alpha beta Receptor IFNAR2 Subunit, Interferon alpha-beta Receptor IFNAR2.1 Subunit, Interferon alpha beta Receptor IFNAR2.1 Subunit, Interferon alpha-beta Receptor IFNAR2.2 Subunit, Interferon alpha beta Receptor IFNAR2.2 Subunit, Interferon alpha-beta Receptor Interferon alpha Receptor Interferon alpha Receptors Interferon alpha beta Receptor Interferon alpha beta Receptor 1 Interferon alpha beta Receptor 2 Interferon alpha beta Receptor Chain 1 Interferon alpha beta Receptor Chain 2 Interferon alpha beta Receptor IFNAR1 Subunit Interferon alpha beta Receptor IFNAR2 Subunit Interferon alpha-beta Receptor Interferon alpha-beta Receptor Chain 1 Interferon alpha-beta Receptor Chain 2 Interferon alpha-beta Receptor IFNAR1 Subunit Interferon alpha-beta Receptor IFNAR2 Subunit Interferon alpha-beta Receptor-1 Interferon alpha-beta Receptor-2 Interferon alphabeta Receptors Receptor, Interferon alpha Receptor, Interferon alpha beta Receptor-1, Interferon alpha-beta Receptor-2, Interferon alpha-beta Receptors, Interferon alpha Receptors, Interferon alphabeta Type I Interferon Receptor alpha Receptor, Interferon alpha Receptors, Interferon alpha-beta Receptor-1, Interferon alpha-beta Receptor-2, Interferon |
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| Tree number(s): |
D12.776.543.750.705.852.400.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D053633 | ||||||
| Scope note: | A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE. |
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| Allowable Qualifiers: |
AD administration & dosage AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CH chemistry CL classification DE drug effects DF deficiency GE genetics HI history IM immunology IP isolation & purification ME metabolism PH physiology RE radiation effects TU therapeutic use UL ultrastructure |
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| Registry Number: | 156986-95-7 | ||||||
| Public MeSH Note: | 2007; INTERFERON ALPHA-BETA RECEPTOR was indexed under MEMBRANE PROTEINS and RECEPTORS, INTERFERON 1994-2006; INTERFERON ALPHA RECEPTOR was indexed under RECEPTORS, INTERFERON 1993-2006 |
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| History Note: | 2007(1993) |
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| DeCS ID: | 52342 | ||||||
| Unique ID: | D053633 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2007/01/01 | ||||||
| Date of Entry: | 2006/07/05 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Receptor, Interferon alpha-beta
- Preferred
Interferon alpha-beta Receptor Chain 2
- Narrower
Interferon alpha-beta Receptor Chain 1
- Narrower
IFNAR2.1 Subunit, Interferon alpha-beta Receptor
- Narrower
IFNAR2.2 Subunit, Interferon alpha-beta Receptor
- Narrower
| Concept UI |
M0231011 |
| Scope note | A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE. |
| Preferred term | Receptor, Interferon alpha-beta |
| Entry term(s) |
IFN alphabetaR IFN-alphaR IFN-alphabetaR Interferon alpha Receptor Interferon alpha Receptors Interferon alpha beta Receptor Interferon alpha-beta Receptor Interferon alphabeta Receptors Receptor, Interferon alpha Receptor, Interferon alpha beta Receptors, Interferon alpha Receptors, Interferon alphabeta Type I Interferon Receptor alpha Receptor, Interferon alpha Receptors, Interferon |
| Concept UI |
M0495180 |
| Preferred term | Interferon alpha-beta Receptor Chain 2 |
| Entry term(s) |
IFNAR2 Subunit, Interferon alpha beta Receptor IFNAR2 Subunit, Interferon alpha-beta Receptor Interferon alpha beta Receptor 2 Interferon alpha beta Receptor Chain 2 Interferon alpha beta Receptor IFNAR2 Subunit Interferon alpha-beta Receptor IFNAR2 Subunit Interferon alpha-beta Receptor-2 Receptor-2, Interferon alpha-beta alpha-beta Receptor-2, Interferon |
| Concept UI |
M0495181 |
| Preferred term | Interferon alpha-beta Receptor Chain 1 |
| Entry term(s) |
IFNAR1 Subunit, Interferon alpha beta Receptor IFNAR1 Subunit, Interferon alpha-beta Receptor Interferon alpha beta Receptor 1 Interferon alpha beta Receptor Chain 1 Interferon alpha beta Receptor IFNAR1 Subunit Interferon alpha-beta Receptor IFNAR1 Subunit Interferon alpha-beta Receptor-1 Receptor-1, Interferon alpha-beta alpha-beta Receptor-1, Interferon |
| Concept UI |
M0495184 |
| Scope note | A shortened cytoplasmic domain variant of the IFNAR2 chain. |
| Preferred term | IFNAR2.1 Subunit, Interferon alpha-beta Receptor |
| Entry term(s) |
IFNAR2.1 Subunit, Interferon alpha beta Receptor |
| Concept UI |
M0495186 |
| Scope note | The full-length variant of the IFNAR2 chain. |
| Preferred term | IFNAR2.2 Subunit, Interferon alpha-beta Receptor |
| Entry term(s) |
IFNAR2.2 Subunit, Interferon alpha beta Receptor |
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