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Descriptor English: Receptor, Interferon alpha-beta
Descriptor Spanish: Receptor de Interferón alfa y beta
Descriptor receptor de interferones alfa y beta
Entry term(s) receptor alfa-beta de interferones
receptor de interferón alfa-beta
Scope note: Receptor heterodimérico que se expresa ubicuamente y que es específico del INTERFERÓN ALFA y del INTEFERÓN BETA. Está compuesto de dos subunidades denominadas IFNAR1 e IFNAR2. Se supone que la subunidad IFNAR2 hace las veces de cadena de unión de ligandos.
Descriptor Portuguese: Receptor de Interferon alfa e beta
Descriptor French: Récepteur à l'interféron alpha-bêta
Entry term(s): IFN alphabetaR
IFN-alphaR
IFN-alphabetaR
IFNAR1 Subunit, Interferon alpha beta Receptor
IFNAR1 Subunit, Interferon alpha-beta Receptor
IFNAR2 Subunit, Interferon alpha beta Receptor
IFNAR2 Subunit, Interferon alpha-beta Receptor
IFNAR2.1 Subunit, Interferon alpha beta Receptor
IFNAR2.1 Subunit, Interferon alpha-beta Receptor
IFNAR2.2 Subunit, Interferon alpha beta Receptor
IFNAR2.2 Subunit, Interferon alpha-beta Receptor
Interferon alpha Receptor
Interferon alpha Receptors
Interferon alpha beta Receptor
Interferon alpha beta Receptor 1
Interferon alpha beta Receptor 2
Interferon alpha beta Receptor Chain 1
Interferon alpha beta Receptor Chain 2
Interferon alpha beta Receptor IFNAR1 Subunit
Interferon alpha beta Receptor IFNAR2 Subunit
Interferon alpha-beta Receptor
Interferon alpha-beta Receptor Chain 1
Interferon alpha-beta Receptor Chain 2
Interferon alpha-beta Receptor IFNAR1 Subunit
Interferon alpha-beta Receptor IFNAR2 Subunit
Interferon alpha-beta Receptor-1
Interferon alpha-beta Receptor-2
Interferon alphabeta Receptors
Receptor, Interferon alpha
Receptor, Interferon alpha beta
Receptor-1, Interferon alpha-beta
Receptor-2, Interferon alpha-beta
Receptors, Interferon alpha
Receptors, Interferon alphabeta
Type I Interferon Receptor
alpha Receptor, Interferon
alpha Receptors, Interferon
alpha-beta Receptor-1, Interferon
alpha-beta Receptor-2, Interferon
Tree number(s): D12.776.543.750.705.852.400.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053633
Scope note: A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Registry Number: 156986-95-7
Public MeSH Note: 2007; INTERFERON ALPHA-BETA RECEPTOR was indexed under MEMBRANE PROTEINS and RECEPTORS, INTERFERON 1994-2006; INTERFERON ALPHA RECEPTOR was indexed under RECEPTORS, INTERFERON 1993-2006
History Note: 2007(1993)
DeCS ID: 52342
Unique ID: D053633
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Receptor, Interferon alpha-beta - Preferred
Concept UI M0231011
Scope note A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.
Preferred term Receptor, Interferon alpha-beta
Entry term(s) IFN alphabetaR
IFN-alphaR
IFN-alphabetaR
Interferon alpha Receptor
Interferon alpha Receptors
Interferon alpha beta Receptor
Interferon alpha-beta Receptor
Interferon alphabeta Receptors
Receptor, Interferon alpha
Receptor, Interferon alpha beta
Receptors, Interferon alpha
Receptors, Interferon alphabeta
Type I Interferon Receptor
alpha Receptor, Interferon
alpha Receptors, Interferon
Interferon alpha-beta Receptor Chain 2 - Narrower
Concept UI M0495180
Preferred term Interferon alpha-beta Receptor Chain 2
Entry term(s) IFNAR2 Subunit, Interferon alpha beta Receptor
IFNAR2 Subunit, Interferon alpha-beta Receptor
Interferon alpha beta Receptor 2
Interferon alpha beta Receptor Chain 2
Interferon alpha beta Receptor IFNAR2 Subunit
Interferon alpha-beta Receptor IFNAR2 Subunit
Interferon alpha-beta Receptor-2
Receptor-2, Interferon alpha-beta
alpha-beta Receptor-2, Interferon
Interferon alpha-beta Receptor Chain 1 - Narrower
Concept UI M0495181
Preferred term Interferon alpha-beta Receptor Chain 1
Entry term(s) IFNAR1 Subunit, Interferon alpha beta Receptor
IFNAR1 Subunit, Interferon alpha-beta Receptor
Interferon alpha beta Receptor 1
Interferon alpha beta Receptor Chain 1
Interferon alpha beta Receptor IFNAR1 Subunit
Interferon alpha-beta Receptor IFNAR1 Subunit
Interferon alpha-beta Receptor-1
Receptor-1, Interferon alpha-beta
alpha-beta Receptor-1, Interferon
IFNAR2.1 Subunit, Interferon alpha-beta Receptor - Narrower
Concept UI M0495184
Scope note A shortened cytoplasmic domain variant of the IFNAR2 chain.
Preferred term IFNAR2.1 Subunit, Interferon alpha-beta Receptor
Entry term(s) IFNAR2.1 Subunit, Interferon alpha beta Receptor
IFNAR2.2 Subunit, Interferon alpha-beta Receptor - Narrower
Concept UI M0495186
Scope note The full-length variant of the IFNAR2 chain.
Preferred term IFNAR2.2 Subunit, Interferon alpha-beta Receptor
Entry term(s) IFNAR2.2 Subunit, Interferon alpha beta Receptor



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