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Descriptor English: Immunoglobulin Light Chains, Surrogate
Descriptor Spanish: Inmunoglobulina de Cadenas Ligeras Subrogadas
Descriptor cadenas ligeras de inmunoglobulinas sustitutas
Entry term(s) cadenas ligeras subrogadas
cadenas ligeras sustituidas
cadenas ligeras sustitutas
cadenas ligeras sustitutas de inmunoglobulinas
seudocadenas ligeras de inmunoglobulinas
sustitutos de cadenas ligeras de inmunoglobulinas
Scope note: Proteína parecida a una cadena ligera de inmunoglobulina que consta de un péptido parecido a la REGIÓN VARIABLE DE LA INMUNOGLOBULINA (como el péptido lambda5 de cadena ligera) y un péptido similar a la REGIÓN CONSTANTE DE LA INMUNOGLOBULINA (como el péptido Vpreb1). Para formar los receptores de las células pre-B se asocian las cadenas ligeras subrogadas con las CADENAS PESADAS DE LA INMUNOGLOBULINA MU, en lugar de las cadenas ligeras de una inmunoglobulina convencional.
Descriptor Portuguese: Cadeias Leves Substitutas da Imunoglobulina
Descriptor French: Pseudochaines légères des immunoglobulines
Entry term(s): Immunoglobulin Light Chain Like lambda5 Peptide
Immunoglobulin Light Chain-Like lambda5 Peptide
Immunoglobulin psiL Chain
Light Chain, Surrogate
Light Chains, Surrogate
Pseudo Immunoglobulin Light Chain
Surrogate Immunoglobulin Light Chains
Surrogate Immunoglobulin kappa Light Chain
Surrogate L Chain Protein
Surrogate Light Chain
Surrogate Light Chains
Surrogate kappa Light Chain
Surrogate lambda Light Chain
VpreB lambda 5 SL Chain
VpreB lambda5 Surrogate Light Chain
VpreB-lambda 5 SL Chain
VpreB-lambda5 Surrogate Light Chain
lambda5 Peptide, Immunoglobulin Light Chain Like
lambda5 Peptide, Immunoglobulin Light Chain-Like
psi lambda Light Chain
psiL Chain, Immunoglobulin
Tree number(s): D12.776.124.486.485.705.750.775
D12.776.124.790.651.705.750.775
D12.776.124.790.651.950.750.500
D12.776.377.715.548.705.750.775
D12.776.377.715.548.950.750.500
D12.776.543.750.705.816.821.750.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054444
Scope note: An immunolglobulin light chain-like protein composed of an IMMUNOGLOBULIN VARIABLE REGION-like peptide (such as light chain like lambda5 peptide) and an IMMUNOGLOBULIN CONSTANT REGION-like peptide (such as Vpreb1 peptide). Surrogate light chains associate with MU IMMUNOGLOBULIN HEAVY CHAINS in place of a conventional immunoglobulin light chains to form pre-B cell receptors.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Immunoglobulin Light Chains (1991-2007)
Public MeSH Note: 2008
History Note: 2008
DeCS ID: 52787
Unique ID: D054444
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2017/06/30
Immunoglobulin Light Chains, Surrogate - Preferred
Concept UI M0229965
Scope note An immunolglobulin light chain-like protein composed of an IMMUNOGLOBULIN VARIABLE REGION-like peptide (such as light chain like lambda5 peptide) and an IMMUNOGLOBULIN CONSTANT REGION-like peptide (such as Vpreb1 peptide). Surrogate light chains associate with MU IMMUNOGLOBULIN HEAVY CHAINS in place of a conventional immunoglobulin light chains to form pre-B cell receptors.
Preferred term Immunoglobulin Light Chains, Surrogate
Entry term(s) Immunoglobulin psiL Chain
Light Chain, Surrogate
Light Chains, Surrogate
Pseudo Immunoglobulin Light Chain
Surrogate Immunoglobulin Light Chains
Surrogate L Chain Protein
Surrogate Light Chain
Surrogate Light Chains
psiL Chain, Immunoglobulin
lambda5 Peptide, Immunoglobulin Light Chain-Like - Narrower
Concept UI M0500358
Preferred term lambda5 Peptide, Immunoglobulin Light Chain-Like
Entry term(s) Immunoglobulin Light Chain Like lambda5 Peptide
Immunoglobulin Light Chain-Like lambda5 Peptide
lambda5 Peptide, Immunoglobulin Light Chain Like
Surrogate Immunoglobulin kappa Light Chain - Narrower
Concept UI M0500449
Preferred term Surrogate Immunoglobulin kappa Light Chain
Entry term(s) Surrogate kappa Light Chain
Surrogate lambda Light Chain - Narrower
Concept UI M0500419
Preferred term Surrogate lambda Light Chain
Entry term(s) VpreB lambda 5 SL Chain
VpreB lambda5 Surrogate Light Chain
VpreB-lambda 5 SL Chain
VpreB-lambda5 Surrogate Light Chain
psi lambda Light Chain



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