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Descriptor English: Primary Myelofibrosis
Descriptor Spanish: Mielofibrosis Primaria
Descriptor mielofibrosis primaria
Scope note: Mieloproliferación de novo derivada de una célula madre anormal. Se caracteriza por el reemplazo de la médula ósea por tejido fibroso, un proceso mediado por las CITOCINAS originadas desde un clon anormal. 
Descriptor Portuguese: Mielofibrose Primária
Descriptor French: Myélofibrose primitive
Entry term(s): Agnogenic Myeloid Metaplasia
Agnogenic Myeloid Metaplasias
Bone Marrow Fibroses
Bone Marrow Fibrosis
Chronic Idiopathic Myelofibrosis
Fibroses, Bone Marrow
Fibrosis, Bone Marrow
Idiopathic Myelofibrosis
Metaplasia, Agnogenic Myeloid
Metaplasia, Myeloid
Metaplasias, Agnogenic Myeloid
Metaplasias, Myeloid
Myelofibroses
Myelofibroses, Primary
Myelofibrosis
Myelofibrosis With Myeloid Metaplasia
Myelofibrosis, Primary
Myeloid Metaplasia
Myeloid Metaplasia, Agnogenic
Myeloid Metaplasias
Myeloid Metaplasias, Agnogenic
Myeloscleroses
Myelosclerosis
Myeloses, Nonleukemic
Myelosis, Nonleukemic
Nonleukemic Myeloses
Nonleukemic Myelosis
Primary Myelofibroses
Tree number(s): C15.378.190.636.765
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D055728
Scope note: A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Myelofibrosis (1963-2008)
Public MeSH Note: 2009; see MYELOID METAPLASIA or MYELOFIBROSIS 1975-2008
History Note: 2009
DeCS ID: 53101
Unique ID: D055728
NLM Classification: WH 380
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2009/01/01
Date of Entry: 2008/07/08
Revision Date: 2013/07/08
Primary Myelofibrosis - Preferred
Concept UI M0519745
Scope note A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.
Preferred term Primary Myelofibrosis
Entry term(s) Agnogenic Myeloid Metaplasia
Agnogenic Myeloid Metaplasias
Bone Marrow Fibroses
Bone Marrow Fibrosis
Chronic Idiopathic Myelofibrosis
Fibroses, Bone Marrow
Fibrosis, Bone Marrow
Idiopathic Myelofibrosis
Metaplasia, Agnogenic Myeloid
Metaplasia, Myeloid
Metaplasias, Agnogenic Myeloid
Metaplasias, Myeloid
Myelofibroses
Myelofibroses, Primary
Myelofibrosis
Myelofibrosis With Myeloid Metaplasia
Myelofibrosis, Primary
Myeloid Metaplasia
Myeloid Metaplasia, Agnogenic
Myeloid Metaplasias
Myeloid Metaplasias, Agnogenic
Myeloscleroses
Myelosclerosis
Myeloses, Nonleukemic
Myelosis, Nonleukemic
Nonleukemic Myeloses
Nonleukemic Myelosis
Primary Myelofibroses



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