Search
Descriptor English: Acid Ceramidase
Descriptor Spanish: Ceramidasa Ácida
Descriptor ceramidasa ácida
Scope note: Subtipo de ceramidasa que es activa en pH ácido. Desempeña un papel importante en la degradación de los esfingolípidos al catalizar la hidrólisis lisosómica de ceramida a esfingosina y ácidos grasos libres. La deficiencia hereditaria de la actividad de la ceramidasa ácida da lugar a la LIPOGRANULOMATOSIS DE FARBER. 
Descriptor Portuguese: Ceramidase Ácida
Descriptor French: Acid Ceramidase
Tree number(s): D08.811.277.087.250.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D055573
Scope note: A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Farber Lipogranulomatosis
Registry Number: EC 3.5.1.23
Previous Indexing: Galactosylgalactosylglucosylceramidase (1974-2008)
Public MeSH Note: 2009; see CERAMIDE TRIHEXOSIDASE 1983-2008
History Note: 2009(1982); use GALACTOSYLGALACTOSYLGLUCOSYLCERAMIDASE 1983-2008
DeCS ID: 53113
Unique ID: D055573
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2009/01/01
Date of Entry: 2008/07/08
Acid Ceramidase - Preferred
Concept UI M0518530
Scope note A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.
Preferred term Acid Ceramidase



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey