CHEMICALS AND DRUGS Chemical Actions and Uses [D27] Chemical Actions and Uses Pharmacologic Actions [D27.505] Pharmacologic Actions Metabolic Side Effects of Drugs and Substances [D27.505.389] Metabolic Side Effects of Drugs and Substances Cytochrome P-450 Enzyme Inhibitors [D27.505.389.500] Cytochrome P-450 Enzyme Inhibitors 14-alpha Demethylase Inhibitors [D27.505.389.500.059] 14-alpha Demethylase Inhibitors Cytochrome P-450 CYP1A2 Inhibitors [D27.505.389.500.120] Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP2B6 Inhibitors [D27.505.389.500.260] Cytochrome P-450 CYP2B6 Inhibitors Cytochrome P-450 CYP2C8 Inhibitors [D27.505.389.500.308] Cytochrome P-450 CYP2C8 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors [D27.505.389.500.315] Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2C19 Inhibitors [D27.505.389.500.319] Cytochrome P-450 CYP2C19 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors [D27.505.389.500.368] Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2E1 Inhibitors [D27.505.389.500.421] Cytochrome P-450 CYP2E1 Inhibitors Cytochrome P-450 CYP3A Inhibitors [D27.505.389.500.503] Cytochrome P-450 CYP3A Inhibitors CHEMICALS AND DRUGS Chemical Actions and Uses [D27] Chemical Actions and Uses Pharmacologic Actions [D27.505] Pharmacologic Actions Molecular Mechanisms of Pharmacological Action [D27.505.519] Molecular Mechanisms of Pharmacological Action Enzyme Inhibitors [D27.505.519.389] Enzyme Inhibitors Cytochrome P-450 Enzyme Inhibitors [D27.505.519.389.335] Cytochrome P-450 Enzyme Inhibitors 14-alpha Demethylase Inhibitors [D27.505.519.389.335.059] 14-alpha Demethylase Inhibitors Cytochrome P-450 CYP1A2 Inhibitors [D27.505.519.389.335.120] Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP2B6 Inhibitors [D27.505.519.389.335.260] Cytochrome P-450 CYP2B6 Inhibitors Cytochrome P-450 CYP2C8 Inhibitors [D27.505.519.389.335.308] Cytochrome P-450 CYP2C8 Inhibitors Cytochrome P-450 CYP2C19 Inhibitors [D27.505.519.389.335.319] Cytochrome P-450 CYP2C19 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors [D27.505.519.389.335.329] Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors [D27.505.519.389.335.368] Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2E1 Inhibitors [D27.505.519.389.335.421] Cytochrome P-450 CYP2E1 Inhibitors Cytochrome P-450 CYP3A Inhibitors [D27.505.519.389.335.503] Cytochrome P-450 CYP3A Inhibitors CHEMICALS AND DRUGS Chemical Actions and Uses [D27] Chemical Actions and Uses Pharmacologic Actions [D27.505] Pharmacologic Actions Molecular Mechanisms of Pharmacological Action [D27.505.519] Molecular Mechanisms of Pharmacological Action Enzyme Inhibitors [D27.505.519.389] Enzyme Inhibitors Steroid Synthesis Inhibitors [D27.505.519.389.870] Steroid Synthesis Inhibitors 14-alpha Demethylase Inhibitors [D27.505.519.389.870.100] 14-alpha Demethylase Inhibitors 5-alpha Reductase Inhibitors [D27.505.519.389.870.200] 5-alpha Reductase Inhibitors Aromatase Inhibitors [D27.505.519.389.870.300] Aromatase Inhibitors CHEMICALS AND DRUGS Chemical Actions and Uses [D27] Chemical Actions and Uses Pharmacologic Actions [D27.505] Pharmacologic Actions Physiological Effects of Drugs [D27.505.696] Physiological Effects of Drugs Hormones, Hormone Substitutes, and Hormone Antagonists [D27.505.696.399] Hormones, Hormone Substitutes, and Hormone Antagonists Hormone Antagonists [D27.505.696.399.450] Hormone Antagonists Steroid Synthesis Inhibitors [D27.505.696.399.450.855] Steroid Synthesis Inhibitors 14-alpha Demethylase Inhibitors [D27.505.696.399.450.855.100] 14-alpha Demethylase Inhibitors 5-alpha Reductase Inhibitors [D27.505.696.399.450.855.200] 5-alpha Reductase Inhibitors Aromatase Inhibitors [D27.505.696.399.450.855.300] Aromatase Inhibitors

14-alpha Demethylase Inhibitors - Preferred

Concept UI	M0545196
Scope note	Compounds that specifically inhibit STEROL 14-DEMETHYLASE. A variety of azole-derived ANTIFUNGAL AGENTS act through this mechanism.
Preferred term	14-alpha Demethylase Inhibitors
Entry term(s)	14 alpha Demethylase Inhibitors 14alpha Demethylase Inhibitors 14alpha-Demethylase Inhibitors CYP51 Inhibitors Inhibitors, 14-alpha Demethylase Inhibitors, 14alpha-Demethylase Inhibitors, CYP51 Lanosterol 14 alpha Demethylase Inhibitors Lanosterol 14 alpha-Demethylase Inhibitors