DeCS

Descriptor English:

Nonsense Mediated mRNA Decay

Descriptor Spanish:

Degradación de ARNm Mediada por Codón sin Sentido

Spanish from Spain

Descriptor	degradación del ARNm mediada por codón sin sentido
Entry term(s)	degradación del ARNm mediada por mutaciones terminadoras
Scope note:	Un proceso metabólico del ARNm que distingue a un normal CODÓN DE TERMINACIÓN de un codón de terminación prematuro (CODÓN SIN SENTIDO) y facilita la rápida degradación del ARNm aberrante que contiene codones de terminación prematuros.

Descriptor Portuguese:

Degradação do RNAm Mediada por Códon sem Sentido

Descriptor French:

Dégradation des ARNm non-sens

Entry term(s):

Decay, Nonsense-Mediated mRNA
Nonsense-Mediated mRNA Decay
mRNA Decay, Nonsense-Mediated

Tree number(s):

G02.111.760.112
G02.111.780.500
G03.839.112
G05.308.700.112

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D059365

Scope note:

An mRNA metabolic process that distinguishes a normal STOP CODON from a premature stop codon (NONSENSE CODON) and facilitates rapid degradation of aberrant mRNAs containing premature stop codons.

Allowable Qualifiers:

DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects

Previous Indexing:

Codon, Nonsense (1999-2011)
RNA, Messenger/metabolism (1994-2011)

Public MeSH Note:

2012

History Note:

2012

RNA Cleavage MeSH

DeCS ID:

54777

Unique ID:

D059365

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

2012/01/01

Date of Entry:

2011/06/24

Revision Date:

2016/06/30

PHENOMENA AND PROCESSES

Chemical Phenomena [G02]

Chemical Phenomena

Biochemical Phenomena [G02.111]

Biochemical Phenomena

RNA Processing, Post-Transcriptional [G02.111.760]

RNA Processing, Post-Transcriptional

Nonsense Mediated mRNA Decay [G02.111.760.112]

Nonsense Mediated mRNA Decay

RNA 3' End Processing [G02.111.760.225]

RNA 3' End Processing

RNA Editing [G02.111.760.250]

RNA Editing

RNA Splicing [G02.111.760.700]

RNA Splicing

PHENOMENA AND PROCESSES

Chemical Phenomena [G02]

Chemical Phenomena

Biochemical Phenomena [G02.111]

Biochemical Phenomena

RNA Stability [G02.111.780]

RNA Stability

Nonsense Mediated mRNA Decay [G02.111.780.500]

Nonsense Mediated mRNA Decay

PHENOMENA AND PROCESSES

Metabolism [G03]

Metabolism

RNA Processing, Post-Transcriptional [G03.839]

RNA Processing, Post-Transcriptional

Nonsense Mediated mRNA Decay [G03.839.112]

Nonsense Mediated mRNA Decay

RNA 3' End Processing [G03.839.225]

RNA 3' End Processing

RNA Editing [G03.839.250]

RNA Editing

RNA Splicing [G03.839.700]

RNA Splicing

PHENOMENA AND PROCESSES

Genetic Phenomena [G05]

Genetic Phenomena

Gene Expression Regulation [G05.308]

Gene Expression Regulation

RNA Processing, Post-Transcriptional [G05.308.700]

RNA Processing, Post-Transcriptional

Nonsense Mediated mRNA Decay [G05.308.700.112]

Nonsense Mediated mRNA Decay

RNA 3' End Processing [G05.308.700.225]

RNA 3' End Processing

RNA Editing [G05.308.700.250]

RNA Editing

RNA Splicing [G05.308.700.700]

RNA Splicing

Nonsense Mediated mRNA Decay - Preferred

Concept UI	M0549615
Scope note	An mRNA metabolic process that distinguishes a normal STOP CODON from a premature stop codon (NONSENSE CODON) and facilitates rapid degradation of aberrant mRNAs containing premature stop codons.
Preferred term	Nonsense Mediated mRNA Decay
Entry term(s)	Decay, Nonsense-Mediated mRNA Nonsense-Mediated mRNA Decay mRNA Decay, Nonsense-Mediated

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