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Descriptor English: N-Terminal Acetyltransferase A
Descriptor Spanish: Acetiltransferasa A N-Terminal
Descriptor N-terminal acetiltransferasa A
Scope note: Subtipo de N-terminal acetiltransferasa que consta de una subunidad catalítica Naa10p y una subunidad auxiliar Naa15p. La estructura de esta enzima se conserva tanto en los eucariotas más inferiores como en los superiores de la escala. Posee especificidad para los residuos N-terminal de SERINA, ALANINA, TREONINA, GLICINA, VALINA y CISTINA, y actúa sobre las cadenas peptídicas nacientes una vez eliminado el iniciador METIONINA por las METIONIL AMINOPEPTIDASAS.
Descriptor Portuguese: Acetiltransferase N-Terminal A
Descriptor French: N-terminal acetyltransferase A
Entry term(s): N Terminal Acetyltransferase A
N Terminal Acetyltransferase Type A
N-Terminal Acetyltransferase Type A
N-Terminal Acetyltransferase, NatA
NatA N Terminal Acetyltransferase
NatA N-Terminal Acetyltransferase
Tree number(s): D08.811.913.050.134.423.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D063209
Scope note: An N-terminal acetyltransferase subtype that consists of the Naa10p catalytic subunit and the Naa15p auxiliary subunit. The structure of this enzyme is conserved between lower and higher eukaryotes. It has specificity for N-terminal SERINE; ALANINE; THREONINE; GLYCINE; VALINE; and CYSTINE residues and acts on nascent peptide chains after the removal of the initiator METHIONINE by METHIONYL AMINOPEPTIDASES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.3.1.88
Previous Indexing: Acetyltransferases (1974-2012)
Public MeSH Note: 2013
History Note: 2013
DeCS ID: 54928
Unique ID: D063209
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
N-Terminal Acetyltransferase A - Preferred
Concept UI M0572111
Scope note An N-terminal acetyltransferase subtype that consists of the Naa10p catalytic subunit and the Naa15p auxiliary subunit. The structure of this enzyme is conserved between lower and higher eukaryotes. It has specificity for N-terminal SERINE; ALANINE; THREONINE; GLYCINE; VALINE; and CYSTINE residues and acts on nascent peptide chains after the removal of the initiator METHIONINE by METHIONYL AMINOPEPTIDASES.
Preferred term N-Terminal Acetyltransferase A
Entry term(s) N Terminal Acetyltransferase A
N Terminal Acetyltransferase Type A
N-Terminal Acetyltransferase Type A
N-Terminal Acetyltransferase, NatA
NatA N Terminal Acetyltransferase
NatA N-Terminal Acetyltransferase



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