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Descriptor English: ATP Binding Cassette Transporter 1
Descriptor Spanish: Transportador 1 de Casete de Unión a ATP
Descriptor transportador de casetes de unión a ATP 1
Entry term(s) transportador 1 de casetes de unión a ATP
transportador ABC 1
Scope note: Superfamilia de proteínas integrales de membrana con dominio de casete de unión al ATP cuyo patrón de expresión es compatible con su participación en el eflujo (salida) de lípidos (colesterol). Está implicada en la ENFERMEDAD DE TANGIER, caracterizada por acumulación de ésteres de colesteril en diversos tejidos.
Descriptor Portuguese: Transportador 1 de Cassete de Ligação de ATP
Descriptor French: Membre-1 de la sous-famille A des transporteurs à cassette liant l'ATP
Entry term(s): ABCA1 Protein
ATP Binding Cassette Sub Family A Member 1
ATP Binding Cassette Transporter, Subfamily A, Member 1
ATP-Binding Cassette Sub-Family A Member 1
CERP Protein
Cholesterol Efflux Regulatory Protein
Cholesterol-Efflux Regulatory Protein
Tree number(s): D09.400.430.890.020.381.500
D12.776.157.530.100.050.500
D12.776.395.550.020.381.500
D12.776.543.550.192.381.500
D12.776.543.585.100.190.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064286
Scope note: A superfamily of integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It is implicated in TANGIER DISEASE, characterized by accumulation of cholesteryl ester in various tissues.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2014; was indexed under ATP-BINDING CASSETTE TRANSPORTERS 2003-2013.
History Note: 2014 (2003)
Related: Tangier Disease MeSH
DeCS ID: 55317
Unique ID: D064286
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 2018/02/28
ATP Binding Cassette Transporter 1 - Preferred
Concept UI M0367387
Scope note A superfamily of integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It is implicated in TANGIER DISEASE, characterized by accumulation of cholesteryl ester in various tissues.
Preferred term ATP Binding Cassette Transporter 1
Entry term(s) ABCA1 Protein
ATP Binding Cassette Sub Family A Member 1
ATP Binding Cassette Transporter, Subfamily A, Member 1
ATP-Binding Cassette Sub-Family A Member 1
CERP Protein
Cholesterol Efflux Regulatory Protein
Cholesterol-Efflux Regulatory Protein



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