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Descriptor English: Ezetimibe
Descriptor Spanish: Ezetimiba
Descriptor ezetimiba
Scope note: Derivado de la azetidina y ANTICOLESTEROMIANTE que inhibe la absorción intestinal de ESTEROLES. Se utiliza para reducir el COLESTEROL total, el LDL COLESTEROL y las APOLIPOPROTEÍNAS B en el tratamiento de las HIPERLIPIDEMIAS.
Descriptor Portuguese: Ezetimiba
Descriptor French: Ézétimibe
Entry term(s): (1-(4-fluorophenyl)-(3R)-(3-(4-fluorophenyl)-(3S)-hydroxypropyl)-(4S)-(4-hydroxyphenyl)-2-azetidinone)
58235, SCH
Ezetimib
Ezetrol
SCH 58235
SCH-58235
SCH58235
Zetia
Tree number(s): D03.383.082.301.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069438
Scope note: An azetidine derivative and ANTICHOLESTEREMIC AGENT that inhibits intestinal STEROL absorption. It is used to reduce total CHOLESTEROL; LDL CHOLESTEROL, and APOLIPOPROTEINS B in the treatment of HYPERLIPIDEMIAS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anticholesteremic Agents
Registry Number: EOR26LQQ24
Public MeSH Note: 2016; EZETIMIBE was indexed under AZETIDINES 1998-2015
History Note: 2016 (1998)
DeCS ID: 55913
Unique ID: D000069438
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2016/05/31
Ezetimibe - Preferred
Concept UI M0422151
Scope note An azetidine derivative and ANTICHOLESTEREMIC AGENT that inhibits intestinal STEROL absorption. It is used to reduce total CHOLESTEROL; LDL CHOLESTEROL, and APOLIPOPROTEINS B in the treatment of HYPERLIPIDEMIAS.
Preferred term Ezetimibe
Entry term(s) (1-(4-fluorophenyl)-(3R)-(3-(4-fluorophenyl)-(3S)-hydroxypropyl)-(4S)-(4-hydroxyphenyl)-2-azetidinone)
Ezetimib
Ezetrol - Narrower
Concept UI M0446922
Preferred term Ezetrol
SCH 58235 - Narrower
Concept UI M0282121
Preferred term SCH 58235
Entry term(s) 58235, SCH
SCH-58235
SCH58235
Zetia - Narrower
Concept UI M0441623
Preferred term Zetia



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