| Descriptor English: | Tadalafil | ||||||
| Descriptor Spanish: | 
                                Tadalafilo                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Tadalafila | ||||||
| Descriptor French: | Tadalafil | ||||||
| Entry term(s): | 
                                    Cialis IC 351 IC-351 IC351 Pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, 6-(1,3- benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-  | 
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| Tree number(s): | 
                                        D03.383.725.150.500 D03.633.100.473.402.111.500 D03.633.300.154.672  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000068581 | ||||||
| Scope note: | A carboline derivative and PHOSPHODIESTERASE 5 INHIBITOR that is used primarily to treat ERECTILE DYSFUNCTION; BENIGN PROSTATIC HYPERPLASIA and PRIMARY PULMONARY HYPERTENSION. | 
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| Allowable Qualifiers: | 
                                                                        AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Pharm Action: | 
                                                                                                    Vasodilator Agents Phosphodiesterase 5 Inhibitors Urological Agents  | 
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| Registry Number: | 742SXX0ICT | ||||||
| CAS Type 1 Name: | Pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, 6-(1,3- benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)- | ||||||
| Public MeSH Note: | 2016; TADALAFIL was indexed under CARBOLINES 2001-2015; and under PHOSPHODIESTERASE INHIBITORS 2001-2003 | 
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| History Note: | 2016 (2001) | 
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| Related: | 
                                                                                                                        Sildenafil Citrate
                                            MeSH                                             | ||||||
| DeCS ID: | 55926 | ||||||
| Unique ID: | D000068581 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2016/01/01 | ||||||
| Date of Entry: | 2015/07/06 | ||||||
| Revision Date: | 2019/02/22 | 
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                                        CHEMICALS AND DRUGS
 
Heterocyclic Compounds [D03]Heterocyclic Compounds - 
                                    
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds - 
                                    
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds 
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                        Tadalafil                                            
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                        IC351                                            
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                        Cialis                                            
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                | Concept UI | 
                                        
                                        M0431130 | 
                                
| Scope note | A carboline derivative and PHOSPHODIESTERASE 5 INHIBITOR that is used primarily to treat ERECTILE DYSFUNCTION; BENIGN PROSTATIC HYPERPLASIA and PRIMARY PULMONARY HYPERTENSION. | 
| Preferred term | Tadalafil | 
| Entry term(s) | 
                                        
                                                                                            Pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, 6-(1,3- benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-                                                 | 
                                
| Concept UI | 
                                        
                                        M0392386 | 
                                
| Preferred term | IC351 | 
| Entry term(s) | 
                                        
                                                                                            IC 351                                                 IC-351  | 
                                
| Concept UI | 
                                        
                                        M0392387 | 
                                
| Preferred term | Cialis | 
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