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Descriptor in English: Axon Initial Segment
Descriptor in Spanish: Segmento Inicial del Axón
Descriptor in Portuguese: Segmento Inicial do Axônio
Descriptor in French: Segment initial de l'axone
Entry term(s): Axon Hillock
Axon Hillocks
Axon Initial Segments
Axonal Trigger Zone
Axonal Trigger Zones
Trigger Zone, Axonal
Tree number(s): A08.675.542.145.250
A11.284.180.075.125
A11.671.137.170
A11.671.501.145.250
Scope note: First segment of axon that connects distal axon segments to the neuronal CELL BODY at the axon hillock region. The axon initial segment is not protected by the MYELIN SHEATH and has properties critical for axonal growth. The axon initial segment and the axon hillock form an axonal trigger zone.
Allowable Qualifiers: CH chemistry
CL classification
DE drug effects
EN enzymology
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
History Note: 2017
DeCS UI: 56260
Descriptor UI: D000071040
Date Established: 2017/01/01
Date of Entry: 2016/06/29
Revision Date: 2016/02/26
Axon Initial Segment - Preferred
Concept UI M000612953
Scope note First segment of axon that connects distal axon segments to the neuronal CELL BODY at the axon hillock region. The axon initial segment is not protected by the MYELIN SHEATH and has properties critical for axonal growth. The axon initial segment and the axon hillock form an axonal trigger zone.
Preferred term Axon Initial Segment
Entry term(s) Axon Initial Segments
Axonal Trigger Zone - Broader
Concept UI M000612957
Preferred term Axonal Trigger Zone
Entry term(s) Axonal Trigger Zones
Trigger Zone, Axonal
Axon Hillock - Related but not broader or narrower
Concept UI M000612956
Preferred term Axon Hillock
Entry term(s) Axon Hillocks



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