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Descriptor English: Stromal Interaction Molecule 1
Descriptor Spanish: Molécula de Interacción Estromal 1
Descriptor molécula de interacción estromal 1
Entry term(s) STIM1
proteína STIM1
Scope note: Molécula de interacción estromal que participa en la regulación de la entrada de calcio tras el agotamiento del calcio intracelular en el RETÍCULO ENDOPLÁSMICO. Al agotarse el calcio se transloca a la membrana plasmática donde activa el CANAL DE CALCIO ACTIVADO POR LA LIBERACIÓN DE CALCIO ORAI1
Descriptor Portuguese: Molécula 1 de Interação Estromal
Descriptor French: Molécule-1 d'interaction stromale
Entry term(s): STIM1 Protein
Tree number(s): D12.776.157.125.806.500
D12.776.543.875.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071737
Scope note: A stromal interaction molecule that functions in the regulation of calcium influx following depletion of intracellular calcium in the ENDOPLASMIC RETICULUM. It translocates to the plasma membrane upon calcium depletion where it activates the CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL ORAI1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Calcium Channels (1996-2016)
Membrane Proteins (1997-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56566
Unique ID: D000071737
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/04/15
Stromal Interaction Molecule 1 - Preferred
Concept UI M000615420
Scope note A stromal interaction molecule that functions in the regulation of calcium influx following depletion of intracellular calcium in the ENDOPLASMIC RETICULUM. It translocates to the plasma membrane upon calcium depletion where it activates the CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL ORAI1.
Preferred term Stromal Interaction Molecule 1
Entry term(s) STIM1 Protein



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