DeCS

Descriptor English:

RNA Recognition Motif

Descriptor Spanish:

Motivo de Reconocimiento de ARN

Spanish from Spain

Descriptor	motivo de reconocimiento de ARN
Entry term(s)	dominio ribonucleoproteico motivo RRM
Scope note:	Motivo de unión al ARN de aproximadamente 80 aminoácidos que consta de cuatro láminas beta antiparalelas superficiales y dos hélices alfa, con una configuración beta-alfa-beta-beta-alfa-beta. Una de las láminas beta de la superficie interactúa con dos o tres bases de ARN específicas. Las interacciones entre otras secuencias y el ARN, así como dentro del motivo de reconocimiento de ARN, aumenta la afinidad y especificidad de la interacción proteína-ARN.

Descriptor Portuguese:

Motivo de Reconhecimento de RNA

Descriptor French:

Motif de reconnaissance de l'ARN

Entry term(s):

RNA Recognition Motifs
RRM Motif
RRM Motifs
Ribonucleoprotein Domain
Ribonucleoprotein Domains

Tree number(s):

G02.111.570.820.709.275.500.869.500

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000071377

Scope note:

An approximately 80 amino acid RNA binding motif that consists of four anti-parallel surface beta sheets and two alpha helices arranged in a beta-alpha-beta-beta-alpha-beta configuration. One of the surface beta sheets interacts with two or three specific RNA bases. Interactions between additional sequences and the RNA, as well as within the RNA recognition motif increase the affinity and specificity of the protein-RNA interaction.

Allowable Qualifiers:

DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects

Previous Indexing:

Amino Acid Sequence (1989-2016)
RNA-Binding Proteins (1991-2016)

Public MeSH Note:

2017

History Note:

2017

RNA Recognition Motif Proteins MeSH

DeCS ID:

56733

Unique ID:

D000071377

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

2017/01/01

Date of Entry:

2016/07/08

Revision Date:

2017/05/12

PHENOMENA AND PROCESSES

Chemical Phenomena [G02]

Chemical Phenomena

Biochemical Phenomena [G02.111]

Biochemical Phenomena

Molecular Structure [G02.111.570]

Molecular Structure

Molecular Conformation [G02.111.570.820]

Molecular Conformation

Protein Conformation [G02.111.570.820.709]

Protein Conformation

Protein Structural Elements [G02.111.570.820.709.275]

Protein Structural Elements

Amino Acid Motifs [G02.111.570.820.709.275.500]

Amino Acid Motifs

RNA-Binding Motifs [G02.111.570.820.709.275.500.869]

RNA-Binding Motifs

Double-Stranded RNA Binding Motif [G02.111.570.820.709.275.500.869.250]

Double-Stranded RNA Binding Motif

RNA Recognition Motif [G02.111.570.820.709.275.500.869.500]

RNA Recognition Motif

RNA Recognition Motif - Preferred

Concept UI	M000613902
Scope note	An approximately 80 amino acid RNA binding motif that consists of four anti-parallel surface beta sheets and two alpha helices arranged in a beta-alpha-beta-beta-alpha-beta configuration. One of the surface beta sheets interacts with two or three specific RNA bases. Interactions between additional sequences and the RNA, as well as within the RNA recognition motif increase the affinity and specificity of the protein-RNA interaction.
Preferred term	RNA Recognition Motif
Entry term(s)	RNA Recognition Motifs RRM Motif RRM Motifs Ribonucleoprotein Domain Ribonucleoprotein Domains

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