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Descriptor English: Hyaluronan Synthases
Descriptor Spanish: Hialuronano Sintasas
Descriptor hialuronano sintasas
Entry term(s) enzima hasA
hialuronano sintasa
hialuronano sintasa 1
hialuronano sintasa 2
hialuronano sintasa 3
hialuronano sintetasa
proteína HAS1
proteína HAS2
proteína HAS3
ácido hialurónico sintetasa
Scope note: Glucuronosiltransferasas asociadas a las mucosas que catalizan la reacción de UDP-N-acetil-D-glucosamina y UDP-D-glucuronato para producir ÁCIDO HIALURÓNICO. La HIALURONANO SINTASA 2 (HAS2) es esencial para la embriogénesis y su expresión en células tumorales se asocia a la presencia de metástasis.
Descriptor Portuguese: Hialuronan Sintases
Descriptor French: Hyaluronan synthases
Entry term(s): 3, Hyaluronan Synthase
HAS1 Protein
HAS2 Protein
HAS3 Protein
Hyaluronan Synthase
Hyaluronan Synthase 1
Hyaluronan Synthase 2
Hyaluronan Synthase 3
Hyaluronan Synthetase
Hyaluronate Synthase
Hyaluronate Synthetase
Hyaluronic Acid Synthetase
Protein, HAS3
Synthase 1, Hyaluronan
Synthase 2, Hyaluronan
Synthase 3, Hyaluronan
Synthase, Hyaluronan
Synthase, Hyaluronate
Synthases, Hyaluronan
Synthetase, Hyaluronan
Synthetase, Hyaluronate
Synthetase, Hyaluronic Acid
hasA Enzyme
Tree number(s): D08.811.913.400.450.480.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000076002
Scope note: Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.4.1.212
Public MeSH Note: 2018; see HYALURONAN SYNTHASE 1976-2017; HYALURONAN SYNTHASES was indexed under GLUCURONOSYLTRANSFERASE 1976-2017
History Note: 2018 (1976); was HYALURONAN SYNTHASE 1976-2017
DeCS ID: 57028
Unique ID: D000076002
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/29
Hyaluronan Synthases - Preferred
Concept UI M000631759
Scope note Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.
Preferred term Hyaluronan Synthases
Entry term(s) Hyaluronan Synthase
Hyaluronan Synthetase
Hyaluronate Synthase
Hyaluronate Synthetase
Hyaluronic Acid Synthetase
Synthase, Hyaluronan
Synthase, Hyaluronate
Synthases, Hyaluronan
Synthetase, Hyaluronan
Synthetase, Hyaluronate
Synthetase, Hyaluronic Acid
Hyaluronan Synthase 3 - Narrower
Concept UI M000633903
Preferred term Hyaluronan Synthase 3
Entry term(s) 3, Hyaluronan Synthase
HAS3 Protein
Protein, HAS3
Synthase 3, Hyaluronan
Hyaluronan Synthase 1 - Narrower
Concept UI M000631778
Preferred term Hyaluronan Synthase 1
Entry term(s) HAS1 Protein
Synthase 1, Hyaluronan
hasA Enzyme - Narrower
Concept UI M000631777
Preferred term hasA Enzyme
Hyaluronan Synthase 2 - Narrower
Concept UI M000631797
Preferred term Hyaluronan Synthase 2
Entry term(s) HAS2 Protein
Synthase 2, Hyaluronan



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