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Descriptor English: Free Radicals
Descriptor Spanish: Radicales Libres
Descriptor Portuguese: Radicais Livres
Descriptor French: Radicaux libres
Entry term(s): Free Radical
Radical, Free
Radicals, Free
Tree number(s): D01.339
D02.389
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005609
Scope note: Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.
Annotation: IM GEN only; usually NIM with coord IM
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Chemistry (1966)
Chemistry, Physical (1966)
Electron Spin Resonance (1966)
Public MeSH Note: 76
History Note: 76(67)
Related: Free Radical Scavengers MeSH
Spin Trapping MeSH
DeCS ID: 5744
Unique ID: D005609
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1976/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27
Free Radicals - Preferred
Concept UI M0008827
Scope note Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.
Preferred term Free Radicals
Entry term(s) Free Radical
Radical, Free
Radicals, Free



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