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Descriptor English: Docetaxel
Descriptor Spanish: Docetaxel
Descriptor docetaxel
Entry term(s) N-debenzoil-N-tert-butoxicarbonil-10-desacetiltaxol
NSC 628503
RP 56976
RP-56976
RP56976
docetaxel anhidro
docetaxol
hidrato de docetaxel
taxoltere metro
taxotere
trihidrato de docetaxel
Scope note: Análogo semisintético del PACLITAXEL que se usa en el tratamiento de las NEOPLASIAS DE LA MAMA y del CARCINOMA PULMONAR NO MICROCÍTICO localmente avanzados o metastásicos.
Descriptor Portuguese: Docetaxel
Descriptor French: Docetaxel
Entry term(s): Docetaxel Anhydrous
Docetaxel Hydrate
Docetaxel Trihydrate
Docetaxol
N Debenzoyl N tert butoxycarbonyl 10 deacetyltaxol
N-Debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol
NSC 628503
RP 56976
RP-56976
RP56976
Taxoltere Metro
Taxotere
Tree number(s): D02.455.426.392.368.242.888.389
D02.455.849.291.850.389
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077143
Scope note: A semisynthetic analog of PACLITAXEL used in the treatment of locally advanced or metastatic BREAST NEOPLASMS and NON-SMALL CELL LUNG CANCER.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Tubulin Modulators
Registry Number: 15H5577CQD
CAS Type 1 Name: Benzenepropanoic acid, beta-(((1,1-dimethylethoxy)carbonyl)amino)-alpha-hydroxy-, (2aR,4S,4aR,6R,9S,11S,12S,12aS,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,4a ,6,11-tetrahydroxy-8,12a,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (alphaR)-, hydrate (1:3)
Public MeSH Note: 2019; DOCETAXEL was indexed under TAXOIDS 1993-2018, and under ALKALOIDS 1991-1992
History Note: 2019 (1991)
DeCS ID: 57515
Unique ID: D000077143
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/07/02
Docetaxel - Preferred
Concept UI M0184558
Scope note A semisynthetic analog of PACLITAXEL used in the treatment of locally advanced or metastatic BREAST NEOPLASMS and NON-SMALL CELL LUNG CANCER.
Preferred term Docetaxel
Entry term(s) Docetaxel Hydrate
Docetaxel Trihydrate
Docetaxol
Taxoltere Metro - Narrower
Concept UI M0357706
Preferred term Taxoltere Metro
RP 56976 - Narrower
Concept UI M0184554
Preferred term RP 56976
Entry term(s) RP-56976
RP56976
Taxotere - Narrower
Concept UI M0184556
Preferred term Taxotere
Docetaxel Anhydrous - Narrower
Concept UI M0585054
Preferred term Docetaxel Anhydrous
Entry term(s) N Debenzoyl N tert butoxycarbonyl 10 deacetyltaxol
N-Debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol
NSC 628503 - Narrower
Concept UI M0184553
Preferred term NSC 628503



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