| Descriptor English: | Quinapril | ||||||
| Descriptor Spanish: | 
                                Quinapril                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Quinapril | ||||||
| Descriptor French: | Quinapril | ||||||
| Entry term(s): | 
                                    2-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid Accupril CI 906 CI-906 PD 109,452 2 PD 109452 2 PD 109452-2 PD 1094522 PD-109,452-2 Quinapril Hydrochloride  | 
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| Tree number(s): | 
                                        D03.633.100.531.820.250 | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000077583 | ||||||
| Scope note: | A tetrahydroisoquinoline derivative and ANGIOTENSIN CONVERTING ENZYME inhibitor that is used in the treatment of HYPERTENSION and HEART FAILURE. | 
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| Allowable Qualifiers: | 
                                                                        AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Pharm Action: | 
                                                                                                    Angiotensin-Converting Enzyme Inhibitors Antihypertensive Agents Cardiovascular Agents  | 
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| Registry Number: | RJ84Y44811 | ||||||
| CAS Type 1 Name: | 3-Isoquinolinecarboxylic acid, 2-((2S)-2-(((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-, (3S)- | ||||||
| Public MeSH Note: | 2019; QUINAPRIL was indexed under TETRAHYDROISOQUINOLINES 2004-2018 and under ISOQUINOLINES 1984-2003 | 
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| History Note: | 2019 (1984) | 
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| DeCS ID: | 57691 | ||||||
| Unique ID: | D000077583 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2019/01/01 | ||||||
| Date of Entry: | 2018/07/09 | ||||||
| Revision Date: | 2018/04/09 | 
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                                        CHEMICALS AND DRUGS
 
Heterocyclic Compounds [D03]Heterocyclic Compounds 
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                        Quinapril                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        2-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Accupril                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        CI 906                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Quinapril Hydrochloride                                            
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                        PD 109452-2                                            
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                | Concept UI | 
                                        
                                        M0122104 | 
                                
| Scope note | A tetrahydroisoquinoline derivative and ANGIOTENSIN CONVERTING ENZYME inhibitor that is used in the treatment of HYPERTENSION and HEART FAILURE. | 
| Preferred term | Quinapril | 
| Concept UI | 
                                        
                                        M000640973 | 
                                
| Preferred term | 2-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid | 
| Concept UI | 
                                        
                                        M0122103 | 
                                
| Preferred term | Accupril | 
| Concept UI | 
                                        
                                        M0122099 | 
                                
| Preferred term | CI 906 | 
| Entry term(s) | 
                                        
                                                                                            CI-906                                                 | 
                                
| Concept UI | 
                                        
                                        M0400670 | 
                                
| Preferred term | Quinapril Hydrochloride | 
| Concept UI | 
                                        
                                        M0122101 | 
                                
| Preferred term | PD 109452-2 | 
| Entry term(s) | 
                                        
                                                                                            PD 109,452 2                                                 PD 109452 2 PD 1094522 PD-109,452-2  | 
                                
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