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Descriptor English: 2-Methoxyestradiol
Descriptor Spanish: 2-Metoxiestradiol
Descriptor 2-metoxiestradiol
Entry term(s) (17 beta)-2-metoxiestra-1,3,5(10)-trieno-3,17-diol
2 metoxiestradiol
2 metoxiestradiol 17 beta
2-(metil-11C)metoxiestradiol
2-metoxiestradiol-17 beta
Panzem
isómero-(17alfa) del 2-metoxiestradiol
Scope note: Metabolito del estradiol que carece de actividad estrogénica y que inhibe la polimerización de la TUBULINA (PROTEÍNA). Posee propiedades antineoplásicas, incluidas la inhibición de la angiogénesis y la inducción de la APOPTOSIS.
Descriptor Portuguese: 2-Metoxiestradiol
Descriptor French: 2-Méthoxyestradiol
Entry term(s): (17 beta)-2-methoxyestra-1,3,5(10)-triene-3,17-diol
2 Methoxyestradiol
2 Methoxyestradiol 17 beta
2 Methoxyoestradiol
2-(methyl-11C)Methoxyestradiol
2-Methoxyestradiol, (17alpha)-isomer
2-Methoxyestradiol-17 beta
2-Methoxyoestradiol
Panzem
Tree number(s): D04.210.500.365.415.248.830
D06.472.334.851.437.500.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077584
Scope note: A metabolite of estradiol that lacks estrogenic activity and inhibits TUBULIN polymerization. It has antineoplastic properties, including inhibition of angiogenesis and induction of APOPTOSIS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Tubulin Modulators
Registry Number: 6I2QW73SR5
CAS Type 1 Name: Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17beta)-
Public MeSH Note: 2019; 2-METHOXYESTRADIOL was indexed under ESTRADIOL/analogs & derivatives 1980-2018
History Note: 2019 (1980)
DeCS ID: 57692
Unique ID: D000077584
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
2-Methoxyestradiol - Preferred
Concept UI M0079449
Scope note A metabolite of estradiol that lacks estrogenic activity and inhibits TUBULIN polymerization. It has antineoplastic properties, including inhibition of angiogenesis and induction of APOPTOSIS.
Preferred term 2-Methoxyestradiol
Entry term(s) (17 beta)-2-methoxyestra-1,3,5(10)-triene-3,17-diol
2 Methoxyestradiol
2 Methoxyoestradiol
2-Methoxyoestradiol
2-Methoxyestradiol-17 beta - Narrower
Concept UI M0079448
Preferred term 2-Methoxyestradiol-17 beta
Entry term(s) 2 Methoxyestradiol 17 beta
2-Methoxyestradiol, (17alpha)-isomer - Narrower
Concept UI M0314942
Preferred term 2-Methoxyestradiol, (17alpha)-isomer
2-(methyl-11C)Methoxyestradiol - Narrower
Concept UI M0515548
Preferred term 2-(methyl-11C)Methoxyestradiol
Panzem - Narrower
Concept UI M0446615
Preferred term Panzem



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